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A New Disease Cluster: Mast Cell Activation Syndrome, Postural Orthostatic Tachycardia Syndrome, and Ehlers-Danlos Syndrome

      Patients with postural orthostatic tachycardia syndrome (POTS) and hypermobility often describe symptoms suggestive of mast cell activation. Herein, we describe a new, unique phenotype, characterized by the co-segregation of three disorders: POTS, Ehlers Danlos syndrome (EDS) and mast cell activation syndrome (MCAS).
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