Increased dietary beta-carotene intake associated with better asthma quality of life

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      We assessed intake of antioxidants in asthmatics to investigate whether asthma quality of life is associated with antioxidants consumption.


      Adult asthmatics were included. Smoking, physical activity, height, weight and peak expiratory flow (PEF) were assessed. “Asthma Life Quality” test (ALQ) and “Asthma Control Questionnaire” (ACQ) were used to evaluate life quality and asthma control. Dietary intake was measured with food frequency questionnaire. Association between ALQ and dietary antioxidants was tested using multivariate analysis of variance design. Nutritional variables were the dependent and ALQ the independent variable (sample was divided into high/low ALQ groups according to median score). In further analysis of variance, results between groups were analyzed by gender and adjusted for energy intake, physical activity, age and BMI.


      We evaluated 31 females and 10 males, aged 38 ± 16 years, with mean BMI 25.8 ± 5.3 (weight/height2). High/low ALQ groups had mean scores respectively of 5.9 ± 4.0 and 14.8 ± 2.4. Mean predicted PEF was 91 ± 11 and 68 ± 20% (p=0.036), and ACQ score was 0.7 ± 0.8 and 2.3 ± 1.4 (p=0.013) respectively for high and low ALQ groups. In female, high ALQ group showed increased consumption of beta-carotene (1822 ± 266 vs. 1039 ± 258 μg, p=0.043), even after adjustment for energy intake and potential confounders (p=0.023). In males, high ALQ group consumed lesser amounts of iron (13.9 ± 2.1 vs. 17.8 ± 2.1 mg, p=0.026; after adjustment for energy intake and confounders, p=0.012). No differences were found for other antioxidants intake both males/females.


      Females with better ALQ had significative increased consumption of beta-carotene, and males consumed lesser amounts of iron, which has pro-oxidant properties.