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Cover 1 page OFC Full-Text PDF (1012 KB)
A Brief Overview of This Month's JACI pages 1A-2A Full-Text PDF (42 KB)
Table of Contents pages 4A-15A Full-Text PDF (280 KB)
Editorial Board page 16A Full Text | Full-Text PDF (43 KB)
Reader services
Information for Readers page 17A Full Text | Full-Text PDF (52 KB)
Footnotes1 pages 18A-21A Full Text | Full-Text PDF (425 KB)
CME Activities Calendar pages 23A-24A Full Text | Full-Text PDF (137 KB)
News beyond our pages
News Beyond Our Pages Marc E. Rothenberg, Harold S. Nelson pages 623-624 Full Text | Full-Text PDF (303 KB)
Reviews and feature articles
Clinical reviews in allergy and immunology
Anaphylaxis: Recent advances in assessment and treatment F. Estelle R. Simons pages 625-636 Abstract | Full Text | Full-Text PDF (901 KB)
Continuing Medical Education examination
Anaphylaxis: Recent advances in assessment and treatment pages 637-638 Full-Text PDF (41 KB)
Mechanisms of allergic diseases
Mechanisms of mast cell signaling in anaphylaxis Dean D. Metcalfe, Richard D. Peavy, Alasdair M. Gilfillan pages 639-646 Abstract | Full Text | Full-Text PDF (464 KB)
Mechanisms of mast cell signaling in anaphylaxis pages 647-648 Full-Text PDF (42 KB)
Editorial
The acetaminophen and asthma hypothesis 10 years on: A case to answer, 22 September 2009 Hamish Farquhar, Julian Crane, Edwin A. Mitchell, Sally Eyers, Richard Beasley pages 649-651 Full Text | Full-Text PDF (74 KB)
Current perspectives
Anaphylaxis syndromes related to a new mammalian cross-reactive carbohydrate determinant Scott P. Commins, Thomas A.E. Platts-Mills pages 652-657 Abstract | Full Text | Full-Text PDF (345 KB)
Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes, 10 August 2009 Shradha Agarwal, Lloyd Mayer pages 658-664 Abstract | Full Text | Full-Text PDF (136 KB)
Rostrum
Recommendations for appropriate sublingual immunotherapy clinical trials, 22 September 2009 Thomas B. Casale, G. Walter Canonica, Jean Bousquet, Linda Cox, Richard Lockey, Harold S. Nelson, Giovanni Passalacqua pages 665-670 Abstract | Full Text | Full-Text PDF (181 KB)
Workshop summary
Summary of the 2008 National Institute of Allergy and Infectious Diseases–US Food and Drug Administration Workshop on Food Allergy Clinical Trial Design, 29 June 2009 Marshall Plaut, Richard T. Sawyer, Matthew J. Fenton pages 671-678.e1 Abstract | Full Text | Full-Text PDF (131 KB)
The Editors' choice
The Editors' Choice Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI pages 679-680 Full Text | Full-Text PDF (265 KB)
Asthma and lower airway disease
Phenotypic determinants of uncontrolled asthma, 10 August 2009 Valérie Siroux, Anne Boudier, Jean Bousquet, Jean-Louis Bresson, Jean-Luc Cracowski, Joane Ferran, Frédéric Gormand, Jocelyne Just, Nicole Le Moual, Sophie Morange, Rachel Nadif, Marie-Pierre Oryszczyn, Christophe Pison, Pierre Scheinmann, Raphaëlle Varraso, Daniel Vervloet, Isabelle Pin, Francine Kauffmann, Epidemiological Study on the Genetics and Environment of Asthma pages 681-687.e3 Abstract | Full Text | Full-Text PDF (333 KB)
Sexual dimorphism: Is it relevant to steroid resistance or asthma control? Gary M. Hunninghake, Diane R. Gold pages 688-690 Full Text | Full-Text PDF (87 KB)
Reports of suicidality in clinical trials of montelukast George Philip, Carolyn Hustad, Gertrude Noonan, Marie-Pierre Malice, Alan Ezekowitz, Theodore F. Reiss, Barbara Knorr pages 691-696.e6 Abstract | Full Text | Full-Text PDF (156 KB)
Assessing risk: Data from montelukast clinical trials Kimberly Kelsay pages 697-698 Full Text | Full-Text PDF (63 KB)
Analysis of behavior-related adverse experiences in clinical trials of montelukast George Philip, Carolyn M. Hustad, Marie-Pierre Malice, Gertrude Noonan, Alan Ezekowitz, Theodore F. Reiss, Barbara Knorr pages 699-706.e8 Abstract | Full Text | Full-Text PDF (259 KB)
Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing, 07 September 2009 John W. Upham, Guicheng Zhang, Angela Rate, Stephanie T. Yerkovich, Merci Kusel, Peter D. Sly, Patrick G. Holt pages 707-713.e2 Abstract | Full Text | Full-Text PDF (221 KB)
Exhaled nitric oxide levels in asthma: Personal best versus reference values, 22 September 2009 Andrew D. Smith, Jan O. Cowan, D. Robin Taylor pages 714-718.e4 Abstract | Full Text | Full-Text PDF (136 KB)
The minimally important difference of the Asthma Control Test, 22 September 2009 Michael Schatz, Mark Kosinski, Aaron S. Yarlas, Jennifer Hanlon, Maria E. Watson, Priti Jhingran pages 719-723.e1 Abstract | Full Text | Full-Text PDF (401 KB)
Rhinitis, sinusitis, and upper airway disease
Modulation by aspirin of nuclear phospho–signal transducer and activator of transcription 6 expression: Possible role in therapeutic benefit associated with aspirin desensitization, 22 September 2009 John W. Steinke, Jeffrey A. Culp, Elizabeth Kropf, Larry Borish pages 724-730.e4 Abstract | Full Text | Full-Text PDF (633 KB)
Domestic use of hypochlorite bleach, atopic sensitization, and respiratory symptoms in adults, 10 August 2009 Jan-Paul Zock, Estel Plana, Josep M. Antó, Geza Benke, Paul D. Blanc, Aurelia Carosso, Anna Dahlman-Höglund, Joachim Heinrich, Deborah Jarvis, Hans Kromhout, Linnéa Lillienberg, Maria C. Mirabelli, Dan Norbäck, Mario Olivieri, Michela Ponzio, Katja Radon, Argo Soon, Marc van Sprundel, Jordi Sunyer, Cecilie Svanes, Kjell Torén, Giuseppe Verlato, Simona Villani, Manolis Kogevinas pages 731-738.e1 Abstract | Full Text | Full-Text PDF (175 KB)
The LOCAL Study: Local reactions do not predict local reactions in allergen immunotherapy, 22 September 2009 Christopher W. Calabria, Christopher A. Coop, Michael S. Tankersley pages 739-744 Abstract | Full Text | Full-Text PDF (107 KB)
Cats and dogs and the risk of atopy in childhood and adulthood, 25 August 2009 Piush J. Mandhane, Malcolm R. Sears, Richie Poulton, Justina M. Greene, W.Y. Wendy Lou, D. Robin Taylor, Robert J. Hancox pages 745-750.e4 Abstract | Full Text | Full-Text PDF (140 KB)
Does exposure to cats and dogs decrease the risk of allergic sensitization and disease? Päivi M. Salo, Darryl C. Zeldin pages 751-752 Full Text | Full-Text PDF (54 KB)
Atopic dermatitis and skin disease
Expression of chemokines and chemokine receptors in lesional and nonlesional upper skin of patients with atopic dermatitis, 22 September 2009 Eva Gros, Caroline Bussmann, Thomas Bieber, Irmgard Förster, Natalija Novak pages 753-760.e1 Abstract | Full Text | Full-Text PDF (859 KB)
Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13 Rui He, Hye Young Kim, Juhan Yoon, Michiko K. Oyoshi, Andrew MacGinnitie, Sho Goya, Eva-Jasmin Freyschmidt, Paul Bryce, Andrew N.J. McKenzie, Dale T. Umetsu, Hans C. Oettgen, Raif S. Geha pages 761-770.e1 Abstract | Full Text | Full-Text PDF (1304 KB)
Food, drug, insect sting allergy, and anaphylaxis
Lipid transfer protein (Ara h 9) as a new peanut allergen relevant for a Mediterranean allergic population, 10 August 2009 Susanne Krause, Gerald Reese, Stefanie Randow, Danila Zennaro, Donato Quaratino, Paola Palazzo, Maria Antonietta Ciardiello, Arnd Petersen, Wolf-Meinhard Becker, Adriano Mari pages 771-778.e5 Abstract | Full Text | Full-Text PDF (1056 KB)
Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma, 22 September 2009 Yuki Hitomi, Motohiro Ebisawa, Morimitsu Tomikawa, Takanori Imai, Takatsugu Komata, Tomomitsu Hirota, Michishige Harada, Masafumi Sakashita, Yoichi Suzuki, Naoki Shimojo, Yoichi Kohno, Kimie Fujita, Akihiko Miyatake, Satoru Doi, Tadao Enomoto, Masami Taniguchi, Noritaka Higashi, Yusuke Nakamura, Mayumi Tamari pages 779-785.e6 Abstract | Full Text | Full-Text PDF (410 KB)
Elevated serum cytokines during human anaphylaxis: Identification of potential mediators of acute allergic reactions, 22 September 2009 Shelley F. Stone, Claire Cotterell, Geoffrey K. Isbister, Anna Holdgate, Simon G.A. Brown, Emergency Department Anaphylaxis Investigators pages 786-792.e4 Abstract | Full Text | Full-Text PDF (462 KB)
Immune deficiencies, infection, and systemic immune disorders
Reduced central tolerance in Omenn syndrome leads to immature self-reactive oligoclonal T cells, 22 September 2009 Raz Somech, Amos J. Simon, Atar Lev, Ilan Dalal, Zvi Spirer, Itamar Goldstein, Meital Nagar, Ninette Amariglio, Gideon Rechavi, Chaim M. Roifman pages 793-800 Abstract | Full Text | Full-Text PDF (743 KB)
Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks, 22 September 2009 Timothy J. Craig, Robyn J. Levy, Richard L. Wasserman, Againdra K. Bewtra, David Hurewitz, Krystyna Obtułowicz, Avner Reshef, Bruce Ritchie, Dumitru Moldovan, Todor Shirov, Vesna Grivcheva-Panovska, Peter C. Kiessling, Heinz-Otto Keinecke, Jonathan A. Bernstein pages 801-808 Abstract | Full Text | Full-Text PDF (200 KB)
Mechanisms of allergy and clinical immunology
Prostaglandin E2–EP3 signaling suppresses skin inflammation in murine contact hypersensitivity, 22 June 2009 Tetsuya Honda, Toshiyuki Matsuoka, Mayumi Ueta, Kenji Kabashima, Yoshiki Miyachi, Shuh Narumiya pages 809-818.e2 Abstract | Full Text | Full-Text PDF (868 KB)
Induction of long-lived allergen-specific plasma cells by mucosal allergen challenge Elke O. Luger, Verena Fokuhl, Michael Wegmann, Melanie Abram, Kati Tillack, Gernot Achatz, Rudolf A. Manz, Margitta Worm, Andreas Radbruch, Harald Renz pages 819-826.e4 Abstract | Full Text | Full-Text PDF (1394 KB)
Critical role of IgE-dependent mast cell activation in a murine model of allergic conjunctivitis, 06 August 2009 Ken Fukuda, Masaharu Ohbayashi, Kei Morohoshi, Lane Zhang, Fu-Tong Liu, Santa J. Ono pages 827-833.e2 Abstract | Full Text | Full-Text PDF (2201 KB)
The occupant as a source of house dust bacteria, 22 September 2009 Martin Täubel, Helena Rintala, Miia Pitkäranta, Lars Paulin, Sirpa Laitinen, Juha Pekkanen, Anne Hyvärinen, Aino Nevalainen pages 834-840.e47 Abstract | Full Text | Full-Text PDF (607 KB)
Letters to the Editor
Anaphylactic reaction to (mixed) fruit juice containing dragon fruit, 13 July 2009 Andreas Kleinheinz, Ute Lepp, Björn M. Hausen, Arnd Petersen, Wolf-Meinhard Becker pages 841-842 Full Text | Full-Text PDF (247 KB)
Induction of IL-10–producing regulatory T cells with TCR diversity by epitope-specific immunotherapy in pollinosis, 25 August 2009 Kei-ichi Yamanaka, Atsushi Yuta, Masato Kakeda, Ryogen Sasaki, Hiroshi Kitagawa, Esteban C. Gabazza, Kimihiro Okubo, Ichiro Kurokawa, Hitoshi Mizutani pages 842-845.e7 Full Text | Full-Text PDF (713 KB)
Serum tryptase levels in atopic and nonatopic children, 10 August 2009 Hirsh D. Komarow, Zonghui Hu, Erica Brittain, Ashraf Uzzaman, Donna Gaskins, Dean D. Metcalfe pages 845-848 Full Text | Full-Text PDF (306 KB)
Polyethylene glycol–modified adenosine deaminase improved lung disease but not liver disease in partial adenosine deaminase deficiency, 10 August 2009 Raz Somech, Yew Hon Lai, Eyal Grunebaum, Nicole Le Saux, Ernest Cutz, Chaim M. Roifman pages 848-850 Full Text | Full-Text PDF (884 KB)
Higher incidence of pediatric anaphylaxis in northern areas of the United States, 25 August 2009 William J. Sheehan, Dionne Graham, Lin Ma, Sachin Baxi, Wanda Phipatanakul pages 850-852.e2 Full Text | Full-Text PDF (210 KB)
Associations between prenatal pesticide exposure and cough, wheeze, and IgE in early childhood, 22 September 2009 Ann Marie Reardon, Matthew S. Perzanowski, Robin M. Whyatt, Ginger L. Chew, Frederica P. Perera, Rachel L. Miller pages 852-854 Full Text | Full-Text PDF (201 KB)
A pilot study of equal doses of 10% IGIV given intravenously or subcutaneously, 22 September 2009 Shilpa H. Desai, Akhil Chouksey, John Poll, Melvin Berger pages 854-856 Full Text | Full-Text PDF (203 KB)
Cyclosporin A reduces CD4+CD25+ regulatory T-cell numbers in patients with atopic dermatitis, 22 September 2009 DirkJan Hijnen, Inge Haeck, Annemieke A. van Kraats, Evert Nijhuis, Marjolein S. de Bruin-Weller, Carla A.F.M. Bruijnzeel-Koomen, Edward F. Knol pages 856-858 Full Text | Full-Text PDF (100 KB)
Correspondence
Vitamin C for the common cold should not be rejected on the basis of old and erroneous articles, 06 August 2009 Harri Hemilä page 859 Full Text | Full-Text PDF (46 KB)
Reply, 06 August 2009 Timothy Mainardi, Simi Kapoor, Leonard Bielory pages 859-860 Full Text | Full-Text PDF (65 KB)
Natural killer T cells in bronchial biopsies from human allergen challenge model of allergic asthma, 22 September 2009 Catherine Reynolds, Julia Barkans, Peter Clark, Harsha Kariyawasam, Daniel Altmann, Barry Kay, Rosemary Boyton pages 860-862 Full Text | Full-Text PDF (476 KB)
Reply, 22 September 2009 Ponpan Matangkasombut, Rosemarie H. DeKruyff, Dale T. Umetsu page 862 Full Text | Full-Text PDF (50 KB)
Thymic stromal lymphopoietin induction by polyinosinic:polycytidylic acid in human keratinocytes is preferentially mediated through protein kinase R and retinoid-inducible gene I and not Toll-like receptor 3, 22 September 2009 Bettina Seidl, Behnam Kalali, Markus Gerhard, Johannes Ring, Markus Ollert, Martin Mempel pages 862-864 Full Text | Full-Text PDF (103 KB)
Reply, 22 September 2009 Toshiro Takai, Anh Tuan Vu, Tuan Anh Le, Hirokazu Kinoshita, Hiroko Ushio, Shigaku Ikeda, Hideoki Ogawa, Ko Okumura pages 864-865 Full Text | Full-Text PDF (55 KB)
The allergy archives: Pioneers and milestones
Discovering anaphylaxis: Elucidation of a shocking phenomenon Sheldon G. Cohen, Joy C. Mazzullo pages 866-869.e1 Full Text | Full-Text PDF (99 KB)
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