The Journal of Allergy and Clinical Immunology
Volume 104, Issue 2 , Pages 301-304 , August 1999

Perennial rhinitis: An independent risk factor for asthma in nonatopic subjects: Results from the European Community Respiratory Health Survey

Received 10 February 1999 ,Revised 31 March 1999 ,Accepted 31 March 1999.

References 

  1. Rowe-Jones JM. The link between the nose and lung, perennial rhinitis and asthma—Is it the same disease?. Allergy. 1997;52(suppl 36):20–28
  2. Vignola AM, Chanes P, Godard P, Bousquet J. Relationships between rhinitis and asthma. Allergy. 1998;53:833–839
  3. Corren J. Allergic rhinitis and asthma: How important is the link?. J Allergy Clin Immunol. 1997;99:S781–S786
  4. Britton J. Is prevention a realistic goal?. In: Book of abstracts. Lancet conference 1997:. the challenge of asthma;. 1997 Oct 8-10;;p. 72; Tours, France
  5. Burrows B, Martinez FD, Halonen M, Barbee RA, Cline MG. Association of asthma with serum IgE levels and skin test reactivity to allergens. N Engl J Med. 1989;320:271–277
  6. Sunyer J, Anto JM, Castellsagué J, Soriano JB, Roca J, the Spanish Group of the European Study of Asthma . Total serum IgE is associated with asthma independently of specific IgE levels. Eur Respir J. 1996;9:1880–1884
  7. Settipane RJ, Hagy GW, Settipane GA. Long-term risk factors for developing asthma and allergic rhinitis: a 23-year follow-up study of college students. Allergy Proc. 1994;15:21–25
  8. Aubier M, Levy J, Clerici C, Neukirch F, Herman D. Different effects of nasal and bronchial glucocorticosteroid administration on bronchial hyperresponsiveness in patients with allergic rhinitis. Am Rev Respir Dis. 1992;53:122–126
  9. Burney PGJ, Luczynska C, Chinn S, Jarvis D. The European Community Respiratory Health Survey. Eur Respir J. 1994;7:954–960
  10. Burney P, Malmberg E, Chinn S, Jarvis D, Luczynska C, Lai E, et al.  The distribution of total and specific serum IgE in the European Community. J Allergy Clin Immunol. 1997;99:314–322
  11. Chinn S, Jarvis D, Luczynska CM, Lai E, Burney PGJ. Measuring atopy in a multi-centre epidemiological study. Eur J Epidemiol. 1996;12:155–162
  12. Droste JHJ, Kerkhof M, DeMonchy JGR, Schouten JP, Rijcken B. Association of skin test reactivity, specific IgE, total IgE, and eosinophils with nasal symptoms in a community-based population study. J Allergy Clin Immunol. 1997;97:922–932
  13. Leone C, Teodoro C, Pelucchi A, Mastropasqua B, Cavigioli G, Marazzini L, et al.  Bronchial responsiveness and airway inflammation in patients with nonallergic rhinitis with eosinophilia syndrome. J Allergy Clin Immunol. 1997;100:775–780
  14. Greisner WA, Settipane RJ, Settipane GA. Co-existence of asthma and allergic rhinitis: a 23-year follow-up study of college students. Allergy Asthma Proc. 1998;19:185–188

 Supported by the European Commission. The following grants helped fund the local studies. Australia: Allen and Hanbury’s, Australia; Belgium: Belgian Science Policy Office and the National Fund for Scientific Research; France: Ministère de la Santé, Glaxo France, Institut Pneumologique d’Aquitaine, Contrat de Plan Etat-Région Languedoc-Roussillon, CNMATS, CNMRT (90MR/10, 91AF/6), the Ministre délégué de la santé, and RNSP; Germany: GSF and the Bundesminister für Forschung und Technologie, Bonn; Greece: The Greek Secretary General of Research and Technology, Fisons, Astra, and Boehringer-Ingelheim; India: Bombay Hospital Trust; Italy: Ministero dell’Univesità e della Ricerca Scientifica e Tecnologica, CNR, Regione Veneto grant RSF n. 381/05.93; New Zealand: Asthma Foundation of New Zealand, Lotteries Grant Board, and the Health Research Council of New Zealand; Norway: Norwegian Research Council project no. 101422/310; Portugal: Glaxo Farmacêutica Lda, Sandoz Portugesa; Spain: Ministero Sanidad y Consumo FIS (grants #91/0016060/OOE-05E., #92/0319, #93/0393), Hospital General de Albacete, Hospital General Juan Ramón Jiménenz, and the Consejeria de Sanidad Principado de Asturias; Sweden: The Swedish Medical Research Council, the Swedish Heart Lung Foundation, the Swedish Association against Asthma and Allergy, The Swedish Society of Medicine, Astra, Glaxo-Wellcome, and Boehringer-Ingelheim; Switzerland: Swiss National Science Foundation grant 4026-28099; UK: National Asthma Campaign, British Lung Foundation, Department of Health, and the South Thames Regional Health Authority; USA: United States Department of Health, Education and Welfare Public Health Service Grant #2 S07 RR05521-28.

☆☆ Reprint requests: Bénédicte Leynaert, PhD, Epidémiologie, Faculté de Médecine Xavier Bichat, BP 416, 75870 Paris Cedex 18, France.

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The Journal of Allergy and Clinical Immunology
Volume 104, Issue 2 , Pages 301-304 , August 1999