The Journal of Allergy and Clinical Immunology
Volume 98, Issue 6, Part 1 , Pages 1051-1057 , December 1996

Noncompliance and treatment failure in children with asthma

Received 6 November 1995 ,Revised 11 April 1996 ,Accepted 6 May 1996.

  • Image Result

    Summary of compliance data for inhaled medications taken over 13 weeks. Percentages of prescribed doses reported to have been taken in patient diaries are compared with doses actually taken documented

    Summary of compliance data for inhaled medications taken over 13 weeks. Percentages of prescribed doses reported to have been taken in patient diaries are compared with doses actually taken documented by Chronolog record (raw compliance) and with doses taken at correct times (time-corrected compliance).

  • Image Result
    Compliance with inhaled corticosteroids: comparison of percentages of prescribed doses actually taken, as recorded by Chronolog (raw compliance), by patients whose asthma was stable throughout the stu

    Compliance with inhaled corticosteroids: comparison of percentages of prescribed doses actually taken, as recorded by Chronolog (raw compliance), by patients whose asthma was stable throughout the study (no oral steroids) with those who required bursts of oral corticosteroids.

  • Image Result
    Days of high use of inhaled β-agonists, as recorded by Chronolog (raw compliance). High use is defined as more than 12 puffs taken in a single day. *Note that the two patients with 13 days of overuse

    Days of high use of inhaled β-agonists, as recorded by Chronolog (raw compliance). High use is defined as more than 12 puffs taken in a single day. *Note that the two patients with 13 days of overuse required hospitalization.

  • Image Result
    Comparison of Chronolog (filled circles) and diary (open circles) data of one patient.

    Comparison of Chronolog (filled circles) and diary (open circles) data of one patient.

  • Image Result
    Comparison of Chronolog (filled circles) and diary (open circles) data of one patient.

    Comparison of Chronolog (filled circles) and diary (open circles) data of one patient.

 From the Departments of aPediatrics and b Biostatistics, National Jewish Center for Immunology and Respiratory Medicine, Denver; and cThe Johns Hopkins Asthma and Allergy Center, Baltimore.

☆☆ Reprint requests: Henry Milgrom, MD, National Jewish Center for Immunology, 1400 Jackson St., Denver, CO 80206.

 0091-6749/96 $5.00 + 0 1/1/75068

PII: S0091-6749(96)80190-4

doi: 10.1016/S0091-6749(96)80190-4

The Journal of Allergy and Clinical Immunology
Volume 98, Issue 6, Part 1 , Pages 1051-1057 , December 1996