The Journal of Allergy and Clinical Immunology
Volume 126, Issue 3 , Pages 648-656.e4 , September 2010

Arabinogalactan isolated from cowshed dust extract protects mice from allergic airway inflammation and sensitization

  • Marcus Peters, PhD

      Affiliations

    • Department of Experimental Pneumology, Ruhr-University Bochum, Bochum, Germany
    • Corresponding Author InformationReprint requests: Marcus Peters, PhD, Department of Experimental Pneumology, Ruhr-University Bochum, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany.
    • ,
  • Marion Kauth, PhD

      Affiliations

    • Department of Experimental Pneumology, Ruhr-University Bochum, Bochum, Germany
    • Protectimmun GmbH, Bochum, Germany
    • ,
  • Olaf Scherner, PhD

      Affiliations

    • Protectimmun GmbH, Bochum, Germany
    • ,
  • Kirsten Gehlhar, PhD

      Affiliations

    • Department of Experimental Pneumology, Ruhr-University Bochum, Bochum, Germany
    • ,
  • Imke Steffen, MSc

      Affiliations

    • Department of Experimental Pneumology, Ruhr-University Bochum, Bochum, Germany
    • ,
  • Pia Wentker, MSc

      Affiliations

    • Department of Experimental Pneumology, Ruhr-University Bochum, Bochum, Germany
    • ,
  • Erika von Mutius, MD

      Affiliations

    • Dr von Hauner Children's Hospital, Munich, Germany
    • ,
  • Otto Holst, PhD

      Affiliations

    • Department of Structural Biochemistry, Research Center Borstel, Borstel, Germany
    • ,
  • Albrecht Bufe, MD, PhD

      Affiliations

    • Department of Experimental Pneumology, Ruhr-University Bochum, Bochum, Germany

Received 7 January 2010 ,Revised 29 April 2010 ,Accepted 7 May 2010.

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 Supported by Deutsche Forschungsgemeinschaft (DFG: BU-762/5-1, HO-1259/4-1), intramural research funding of Ruhr-University Bochum (FoRUM 476-2005), the European Commission as part of GABRIEL (a multidisciplinary study to identify the genetic and environmental causes of asthma in the European Community), and Protectimmun GmbH.

 Disclosure of potential conflict of interest: E. von Mutius has consulted for Glaxo SmithKline, UCB, and Protectimmun and has received research support from Airsonett AB. O. Holst has received research support from Deutsche Forschungsgemeinschaft and the European Union. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(10)00812-2

doi: 10.1016/j.jaci.2010.05.011

The Journal of Allergy and Clinical Immunology
Volume 126, Issue 3 , Pages 648-656.e4 , September 2010

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