The Journal of Allergy and Clinical Immunology
Volume 125, Issue 1 , Pages 209-216 , January 2010

Defect of regulatory T cells in patients with Omenn syndrome

  • Barbara Cassani, PhD

      Affiliations

    • Fondazione Humanitas per la Ricerca, Rozzano (MI), Italy
    • ,
  • Pietro Luigi Poliani, MD, PhD

      Affiliations

    • Department of Pathology, University of Brescia, Brescia, Italy
    • ,
  • Daniele Moratto, PhD

      Affiliations

    • Istituto di Medicina Molecolare “Angelo Nocivelli,” Department of Pediatrics, University of Brescia, Brescia, Italy
    • ,
  • Cristina Sobacchi, PhD

      Affiliations

    • CNR-Istituto Tecnologie Biomediche, Segrate (MI), Italy
    • IRCCS Istituto Clinico Humanitas, Rozzano (MI), Italy
    • ,
  • Veronica Marrella, PhD

      Affiliations

    • CNR-Istituto Tecnologie Biomediche, Segrate (MI), Italy
    • IRCCS Istituto Clinico Humanitas, Rozzano (MI), Italy
    • ,
  • Laura Imperatori, PhD

      Affiliations

    • Istituto di Medicina Molecolare “Angelo Nocivelli,” Department of Pediatrics, University of Brescia, Brescia, Italy
    • ,
  • Donatella Vairo, PhD

      Affiliations

    • Istituto di Medicina Molecolare “Angelo Nocivelli,” Department of Pediatrics, University of Brescia, Brescia, Italy
    • ,
  • Alessandro Plebani, MD

      Affiliations

    • Istituto di Medicina Molecolare “Angelo Nocivelli,” Department of Pediatrics, University of Brescia, Brescia, Italy
    • ,
  • Silvia Giliani, PhD

      Affiliations

    • Istituto di Medicina Molecolare “Angelo Nocivelli,” Department of Pediatrics, University of Brescia, Brescia, Italy
    • ,
  • Paolo Vezzoni, MD

      Affiliations

    • CNR-Istituto Tecnologie Biomediche, Segrate (MI), Italy
    • IRCCS Istituto Clinico Humanitas, Rozzano (MI), Italy
    • ,
  • Fabio Facchetti, MD, PhD

      Affiliations

    • Department of Pathology, University of Brescia, Brescia, Italy
    • ,
  • Fulvio Porta, MD

      Affiliations

    • Istituto di Medicina Molecolare “Angelo Nocivelli,” Department of Pediatrics, University of Brescia, Brescia, Italy
    • ,
  • Luigi D. Notarangelo, MD

      Affiliations

    • Division of Immunology, Children's Hospital, Boston, Mass
    • Manton Center for Orphan Disease Research, Children's Hospital, Boston, Mass
    • ,
  • Anna Villa, MD

      Affiliations

    • CNR-Istituto Tecnologie Biomediche, Segrate (MI), Italy
    • San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy
    • These authors share senior authorship of this work.
    • Corresponding Author InformationReprint requests: Anna Villa MD, ITB-CNR, via F.lli Cervi 90, Segrate, Milan, Italy.
    • ,
  • Raffaele Badolato, MD, PhD

      Affiliations

    • Istituto di Medicina Molecolare “Angelo Nocivelli,” Department of Pediatrics, University of Brescia, Brescia, Italy
    • These authors share senior authorship of this work.

Received 4 May 2009 ,Revised 22 September 2009 ,Accepted 16 October 2009.

References 

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 This work was supported by grants from the Italian Telethon Foundation to A.V., from Fondazione Cariplo (Nobel project to A.V., and L.D.N./R.B.), Fondazione Cariplo to A.V. and P.L.P., EU grant FP7 HLH-cure (project n. 201461), PRIN 2007 n. 2007ACZMMZ_005, Telethon GGP07241 to R.B., grant FIRB/MIUR (n. RBIN04CHXT) to P.V., Ministero della Salute RF2007 Giovani Ricercatori Grant to C.S., and the Manton Foundation to L.D.N.

 Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.

PII: S0091-6749(09)01551-6

doi: 10.1016/j.jaci.2009.10.023

The Journal of Allergy and Clinical Immunology
Volume 125, Issue 1 , Pages 209-216 , January 2010

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