The Journal of Allergy and Clinical Immunology
Volume 124, Issue 6 , Pages 1251-1258.e23 , December 2009

Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three

  • Joseph A. Odhiambo, MMed

      Affiliations

    • Centre for Respiratory Diseases Research, Kenya Medical Research Institute, Nairobi, Kenya
    • ,
  • Hywel C. Williams, PhD

      Affiliations

    • Centre for Evidence Based Dermatology, University of Nottingham, Nottingham, United Kingdom
    • ,
  • Tadd O. Clayton, MSc

      Affiliations

    • Department of Paediatrics: Child and Youth Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    • Corresponding Author InformationReprint requests: Tadd O. Clayton, MSc, Department of Paediatrics: Child and Youth Health Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
    • ,
  • Colin F. Robertson, MD

      Affiliations

    • Murdoch Children's Research Institute, Melbourne, Australia
    • ,
  • M. Innes Asher, MBChB

      Affiliations

    • Department of Paediatrics: Child and Youth Health, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    • ,
  • ISAAC Phase Three Study Group

Received 2 July 2009 ,Revised 4 October 2009 ,Accepted 7 October 2009.

  • Image Result

    World maps showing prevalence of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Blue squares indicate prevalence of less than 5%

    World maps showing prevalence of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Blue squares indicate prevalence of less than 5%, green circles indicate prevalence of 5% to less than 10%, yellow diamonds indicate prevalence of 10% to less than 15%, and red stars indicate prevalence of 15% or more. Europe is shown in greater detail in the inset section.

  • Image Result
    Ranked prevalence plots of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

    Ranked prevalence plots of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

  • Image Result
    Ranked prevalence plots of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

    Ranked prevalence plots of current symptoms of eczema for the age group 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

  • Image Result
    Questions on eczema symptoms used in ISAAC Phase Three.

    Questions on eczema symptoms used in ISAAC Phase Three.

  • Image Result
    World maps showing prevalence of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Blue squares indicate prevalence of less

    World maps showing prevalence of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Blue squares indicate prevalence of less than 1%, green circles indicate prevalence of 1% to less than 1.5%, yellow diamonds indicate prevalence of 1.5% to less than 2%, and red stars indicate prevalence of 2% or more. Europe is shown in greater detail in the inset section.

  • Image Result
    Ranked prevalence plots of current symptoms of eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Regions are ordered by average prevalence.

    Ranked prevalence plots of current symptoms of eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Regions are ordered by average prevalence.

  • Image Result
    Ranked prevalence plots of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

    Ranked prevalence plots of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

  • Image Result
    Ranked prevalence plots of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

    Ranked prevalence plots of current symptoms of severe eczema for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

  • Image Result
    Ranked prevalence plots of lifetime reported “eczema” for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

    Ranked prevalence plots of lifetime reported “eczema” for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

  • Image Result
    Ranked prevalence plots of lifetime reported “eczema” for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

    Ranked prevalence plots of lifetime reported “eczema” for the age groups 6 to 7 years (A) and 13 to 14 years (B). Each symbol represents a center. Countries are ordered by average prevalence.

  • Image Result
    Scatter plots illustrating prevalence by sex for current symptoms of eczema (A), current symptoms of severe eczema (B), and lifetime reported “eczema” (C) for the age group 6 to 7 years, and current s

    Scatter plots illustrating prevalence by sex for current symptoms of eczema (A), current symptoms of severe eczema (B), and lifetime reported “eczema” (C) for the age group 6 to 7 years, and current symptoms of eczema (D), current symptoms of severe eczema (E), and lifetime reported “eczema” (F) for the age group 13 to 14 years. Each symbol represents a center. The line of equality is shown on each plot.

  • Image Result
    Scatter plots illustrating prevalence by sex for current symptoms of eczema (A), current symptoms of severe eczema (B), and lifetime reported “eczema” (C) for the age group 6 to 7 years, and current s

    Scatter plots illustrating prevalence by sex for current symptoms of eczema (A), current symptoms of severe eczema (B), and lifetime reported “eczema” (C) for the age group 6 to 7 years, and current symptoms of eczema (D), current symptoms of severe eczema (E), and lifetime reported “eczema” (F) for the age group 13 to 14 years. Each symbol represents a center. The line of equality is shown on each plot.

 Currently the main source of funding for the ISAAC International Data Centre (IIDC) is the BUPA Foundation. Many New Zealand funding bodies have contributed support for the IIDC during the periods of fieldwork and data compilation (the Health Research Council of New Zealand, the Asthma and Respiratory Foundation of New Zealand, the Child Health Research Foundation, the Hawke's Bay Medical Research Foundation, the Waikato Medical Research Foundation, Glaxo Wellcome New Zealand, the NZ Lottery Board, and Astra Zeneca New Zealand). Glaxo Wellcome International Medical Affairs supported the regional coordination for Phase Three and the IIDC.

 Disclosure of potential conflict of interest: T. O. Clayton and M. I. Asher have received research support from the BUPA Foundation (UK). C. F. Robertson has received research support from the National Health Medical Research Council. J. A. Odhiambo and H. C. Williams have declared that they have no conflict of interest.

PII: S0091-6749(09)01535-8

doi: 10.1016/j.jaci.2009.10.009

The Journal of Allergy and Clinical Immunology
Volume 124, Issue 6 , Pages 1251-1258.e23 , December 2009

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