The Journal of Allergy and Clinical Immunology
Volume 124, Issue 6 , Pages 1351-1352 , December 2009

Adverse reactions during peanut oral immunotherapy home dosing

  • Pooja Varshney, MD

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC
    • ,
  • Pamela H. Steele, CPNP

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC
    • ,
  • Brian P. Vickery, MD

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC
    • ,
  • J. Andrew Bird, MD

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC
    • ,
  • Ananth Thyagarajan, MD

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC
    • ,
  • Amy M. Scurlock, MD

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Ark
    • ,
  • Tamara T. Perry, MD

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Ark
    • ,
  • Stacie M. Jones, MD

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Ark
    • ,
  • A. Wesley Burks, MD

      Affiliations

    • Pediatric Allergy and Immunology, Department of Pediatrics, Duke University Medical Center, Durham, NC

References 

  1. Jones SM, Pons L, Roberts JL, Scurlock AM, Perry TT, Kulis M, et al. Clinical efficacy and immune regulation with peanut oral immunotherapy. J Allergy Clin Immunol. 2009;124:292–300e1-97
  2. Hofmann AM, Scurlock AM, Jones SM, Palmer KP, Lokhnygina Y, Steele PH, et al. Safety of a peanut oral immunotherapy protocol in children with peanut allergy. J Allergy Clin Immunol. 2009;124:286–291e1-6
  3. Cox L, Li JT, Nelson H, Lockey R. Allergen immunotherapy: a practice parameter second update. J Allergy Clin Immunol. 2007;120(suppl):S25–S85
  4. Staden U, Rolinck-Werninghaus C, Brewe F, Wahn U, Niggemann B, Beyer K. Specific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction. Allergy. 2007;62:1261–1269
  5. Meglio P, Bartone E, Plantamura M, Arabito E, Giampietro PG. A protocol for oral desensitization in children with IgE-mediated cow's milk allergy. Allergy. 2004;59:980–987
  6. Skripak JM, Nash SD, Rowley H, Brereton NH, Oh S, Hamilton RG, et al. A randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow's milk allergy. J Allergy Clin Immunol. 2008;122:1154–1160

 Disclosure of potential conflict of interest: P. Varshney received the National Institutes of Health T32 Training Grant. B. P. Vickery has received research support from the Thrasher Research Foundation. J. A. Bird has received research support from the Food Allergy Initiative. A. M. Scurlock has received research support from the National Institutes of Health. T. T. Perry has received research support from the National Institutes of Health and the Robert Wood Johnson Foundation. S. M. Jones is a consultant for and board member of the Food Allergy & Anaphylaxis Network and has received research support from the National Institutes of Health and DYAX Corporation. A. W. Burks is a Consultant for ActoGeniX NV, Intelliject, McNeil Nutritionals, and Novartis; is a minority stockholder of Allertein and MastCell, Inc; is on the Advisory Board for Dannon Co. Probiotics; is on the Expert Panel for Nutricia; has received research support from the National Institutes of Health, the Food Allergy & Anaphylaxis Network, and the Wallace Research Foundation; has served as an expert witness on the topic of food allergies; is on the Medical Board of Directors for the Food Allergy & Anaphylaxis Network and the Dermatological Allergy Committee for the American College of Allergy, Asthma & Immunology; is a member for the National Institutes of Health Hypersensitivity, Autoimmune and Immune-mediated Disease Study Section; and is on the Journal of Allergy and Clinical Immunology reviewer board. The rest of the authors have declared they have no conflict of interest.

PII: S0091-6749(09)01461-4

doi: 10.1016/j.jaci.2009.09.042

The Journal of Allergy and Clinical Immunology
Volume 124, Issue 6 , Pages 1351-1352 , December 2009

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