The Journal of Allergy and Clinical Immunology
Volume 124, Issue 6 , Pages 1235-1244.e58 , December 2009

Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis

  • Emma Guttman-Yassky, MD, MSc

      Affiliations

    • Laboratory for Investigative Dermatology, Rockefeller University, New York, NY
    • Department of Dermatology, Weill-Cornell Medical College, Cornell University, New York, NY
    • These authors contributed equally to this work.
    • ,
  • Mayte Suárez-Fariñas, PhD

      Affiliations

    • Laboratory for Investigative Dermatology, Rockefeller University, New York, NY
    • These authors contributed equally to this work.
    • ,
  • Andrea Chiricozzi, MD

      Affiliations

    • Laboratory for Investigative Dermatology, Rockefeller University, New York, NY
    • Department of Dermatology, University of Rome “Tor Vergata”, Rome, Italy
    • ,
  • Kristine E. Nograles, MD

      Affiliations

    • Laboratory for Investigative Dermatology, Rockefeller University, New York, NY
    • ,
  • Avner Shemer, MD

      Affiliations

    • Tel-Hashomer Hospital and Tel-Aviv University, Tel-Aviv, Israel
    • ,
  • Judilyn Fuentes-Duculan, MD

      Affiliations

    • Laboratory for Investigative Dermatology, Rockefeller University, New York, NY
    • ,
  • Irma Cardinale, MSc

      Affiliations

    • Laboratory for Investigative Dermatology, Rockefeller University, New York, NY
    • ,
  • Peng Lin, BSc

      Affiliations

    • Department of Genetics, Washington University School of Medicine, St Louis, Mo
    • ,
  • Reuven Bergman, MD

      Affiliations

    • Rambam Medical Center and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    • ,
  • Anne M. Bowcock, PhD

      Affiliations

    • Department of Genetics, Washington University School of Medicine, St Louis, Mo
    • ,
  • James G. Krueger, MD, PhD

      Affiliations

    • Laboratory for Investigative Dermatology, Rockefeller University, New York, NY
    • Corresponding Author InformationReprint requests: James G. Krueger, MD, PhD, Laboratory for Investigative Dermatology, Rockefeller University, 1230 York Avenue, New York, NY 10065.

Received 4 August 2009 ,Revised 15 September 2009 ,Accepted 17 September 2009.

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 Supported by grant number 5UL1RR024143-02 from the National Center for Research Resources, a component of the National Institutes of Health, and the National Institutes of Health Roadmap for Medical Research.

 Disclosure of potential conflict of interest: J. G. Krueger has received research support from Centocor, Amgen, and Wyeth. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(09)01432-8

doi: 10.1016/j.jaci.2009.09.031

The Journal of Allergy and Clinical Immunology
Volume 124, Issue 6 , Pages 1235-1244.e58 , December 2009

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