The Journal of Allergy and Clinical Immunology
Volume 124, Issue 5 , Pages 928-932.e1 , November 2009

Diagnostic properties of inhaled mannitol in the diagnosis of asthma: A population study

Received 23 October 2008 ,Revised 19 June 2009 ,Accepted 23 June 2009.

  • Image Result

    Reactivity to mannitol in a random population sample of asthmatic and nonasthmatic subjects. The 2 dotted lines represent cutoff points at a 10% or 15% decrease in FEV1.

    Reactivity to mannitol in a random population sample of asthmatic and nonasthmatic subjects. The 2 dotted lines represent cutoff points at a 10% or 15% decrease in FEV1.

  • Image Result

    ROC curve. The curve visualizes reactivity to mannitol, given in RDR, against the diagnosis of current asthma.

    ROC curve. The curve visualizes reactivity to mannitol, given in RDR, against the diagnosis of current asthma.

 The Danish Agency for Science, Technology and Innovation, an institution under the Danish Ministry of Science, Technology and Innovation, granted a 1-year scholarship. Pharmaxis provided the research team with an unrestricted grant, with which one of the research assistants was employed. Moreover, parts of the Mannitol kits were delivered at no cost by Pharmaxis.

 Disclosure of potential conflict of interest: V. Backer has received research support from Pharmaxis. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(09)00984-1

doi: 10.1016/j.jaci.2009.06.028

The Journal of Allergy and Clinical Immunology
Volume 124, Issue 5 , Pages 928-932.e1 , November 2009