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The Journal of Allergy and Clinical Immunology
Volume 124, Issue 2
, Pages 230-237.e4
, August 2009
Leptin and leptin receptor expression in asthma
References
- . Leptin and adipocytokines: bridging the gap between immunity and atherosclerosis. Curr Pharm Des. 2007;13:3676–3680
- . Leptin is an eosinophil survival factor. J Allergy Clin Immunol. 2005;116:1228–1234
- . Apoptotic pathways are inhibited by leptin receptor activation in neutrophils. J Immunol. 2005;174:8090–8096
- Does leptin play a cytokine-like role within the airways of COPD patients?. Eur Respir J. 2005;26:398–405
- . Leptin and wound inflammation in diabetic ob/ob mice: differential regulation of neutrophil and macrophage influx and a potential role for the scab as a sink for inflammatory cells and mediators. Diabetes. 2003;52:2821–2832
- . Identification of leptin receptors in lung and isolated fetal type II cells. Am J Respir Cell Mol Biol. 2002;27:71–77
- . Leptin receptor and functional effects of leptin in human endothelial progenitor cells. Atherosclerosis. 2005;183:131–139
- . Effect of leptin on allergic airway responses in mice. J Allergy Clin Immunol. 2005;115:103–109
- . Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases. Eur Respir J. 2008;32:1068–1081
- . Clinical relevance of airway remodelling in airway diseases. Eur Respir J. 2007;30:134–155
- . Remodelling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med. 2001;164(suppl):S28–S38
- . Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodelling. J Allergy Clin Immunol. 2003;111(suppl):S18–S34
- . Is asthma a fibrotic disease?. Chest. 1995;107(suppl):111s–117s
- . Tissue remodelling as a feature of persistent asthma. J Allergy Clin Immunol. 2000;105:1041–1053
- Transforming growth factor-β expression in mucosal biopsies in asthma and chronic bronchitis. Am J Respir Crit Care Med. 1997;156:591–599
- In vitro effects of flunisolide on MMP-9, TIMP-1, fibronectin, TGF-beta1 release and apoptosis in sputum cells freshly isolated from mild to moderate asthmatics. Allergy. 2004;59:927–932
- . Severe asthma is an epithelial disease. Eur Respir J. 2005;25:945–946
- Severe asthma in adults: what are the important questions?. J Allergy Clin Immunol. 2007;119:1337–1348
- . Hormonal regulation of leptin mRNA expression and preadipocyte recruitment and differentiation in porcine primary cultures of S-V cells. Obes Res. 1998;6:164–172
- . Acute and chronic regulation of leptin synthesis, storage, and secretion by insulin and dexamethasone in human adipose tissue. Am J Physiol Endocrinol Metab. 2007;292:E858–E864
- . Directional secretion and transport of leptin and expression of leptin receptor isoforms in human placental BeWo cells. Mol Cell Endocrinol. 2005;241:73–79
- CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol. 1994;10:38–47
- Global Initiative for Asthma (GINA). Available at: www.ginasthma.org. Accessed 2008.
- . Development and validation of a questionnaire to measure asthma control. Eur Respir J. 1999;14:902–907
- Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med. 1997;337:1405–1411
- Comparison between nasal and bronchial inflammation in asthmatic and control subjects. Am J Respir Crit Care Med. 1999;159:588–595
- . Leptin and the obesity receptor (OB-R) in the small intestine and colon: a colocalization study. J Histochem Cytochem. 2008;56:677–685
- . Prolactin affects leptin action in the bovine mammary gland via the mammary fat pad. J Endocrinol. 2006;191:407–413
- . Basic mechanisms of development of airway structural changes in asthma. Eur Respir J. 2007;29:379–389
- . The airway epithelium is central to the pathogenesis of asthma. Allergol Int. 2008;57:1–10
- . Specificity of basement membrane thickening in severe asthma. J Allergy Clin Immunol. 2007;119:1367–1374
- Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta 1: potential role in idiopathic pulmonary fibrosis. Am J Pathol. 2005;166:1321–1332
- Increased TGF-beta2 in severe asthma with eosinophilia. J Allergy Clin Immunol. 2005;115:110–117
- . Subepithelial basement membrane immunoreactivity for matrix metalloproteinase 9: association with asthma severity, neutrophilic inflammation, and wound repair. J Allergy Clin Immunol. 2003;111:1345–1352
- . Epithelial dysfunction in asthma. J Allergy Clin Immunol. 2007;120:1233–1244
- . The airway epithelium: structural and functional properties in health and disease. Respirology. 2003;8:432–446
- . Leptin mediates the parathyroid hormone-related protein paracrine stimulation of fetal lung maturation. Am J Physiol Lung Cell Mol Physiol. 2002;282:L405–L410
- Airway inflammation and basement membrane tenascin in newly diagnosed atopic and nonatopic asthma. Respir Med. 2003;97:1045–1051
Supported by INSERM-CNR contract.
Disclosure of potential conflict of interest: P. Chanez has received research support from Schering-Plough and has served as an advisor for all of the respiratory drug companies. The rest of the authors have declared that they have no conflict of interest.
PII: S0091-6749(09)00691-5
doi: 10.1016/j.jaci.2009.04.032
© 2009 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
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The Journal of Allergy and Clinical Immunology
Volume 124, Issue 2
, Pages 230-237.e4
, August 2009
