The Journal of Allergy and Clinical Immunology
Volume 124, Issue 1 , Pages 45-51.e4, July 2009

Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction

  • Marta Kaminska, MD

      Affiliations

    • Meakins-Christie Laboratories, Montreal, Quebec, Canada
    • ,
  • Susan Foley, MD

      Affiliations

    • Meakins-Christie Laboratories, Montreal, Quebec, Canada
    • ,
  • Karim Maghni, DSc, PhD

      Affiliations

    • Centre de Recherche de l'Hopital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada
    • ,
  • Claudine Storness-Bliss, BSc

      Affiliations

    • Department of Radiology and the James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Vancouver General Hospital, Vancouver, British Columbia, Canada
    • ,
  • Harvey Coxson, PhD

      Affiliations

    • Department of Radiology and the James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Vancouver General Hospital, Vancouver, British Columbia, Canada
    • ,
  • Heberto Ghezzo, PhD

      Affiliations

    • Meakins-Christie Laboratories, Montreal, Quebec, Canada
    • ,
  • Catherine Lemière, MD, MSc

      Affiliations

    • Centre de Recherche de l'Hopital du Sacré-Coeur de Montréal, Montreal, Quebec, Canada
    • ,
  • Ronald Olivenstein, MD

      Affiliations

    • Meakins-Christie Laboratories, Montreal, Quebec, Canada
    • ,
  • Pierre Ernst, MD

      Affiliations

    • Meakins-Christie Laboratories, Montreal, Quebec, Canada
    • ,
  • Qutayba Hamid, MD, PhD

      Affiliations

    • Meakins-Christie Laboratories, Montreal, Quebec, Canada
    • ,
  • James Martin, MD, DSc

      Affiliations

    • Meakins-Christie Laboratories, Montreal, Quebec, Canada
    • Corresponding Author InformationReprint requests: James Martin, MD, DSc, Meakins Christie Laboratories, 3626 St Urbain, Montreal, Quebec, Canada, H2X 2P2.

Received 31 July 2008; received in revised form 4 March 2009; accepted 16 March 2009. published online 01 June 2009.

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    •  Supported by the Richard and Edith Strauss Canada Foundation, Canadian Institutes of Health Research.

     Disclosure of potential conflict of interest: H. Coxson has served as a consultant/advisor board member for GlaxoSmithKline and has received research support fro GlaxoSmithKline, Spiration, and Wyeth. C. Lemière has received research support from the National Institute for Occupational Safety and Health and the Institut de Recherche Robert-Sauvé en Santé et Sécurité du Travail and has served as an advisor to GlaxoSmithKline, AstraZeneca, and Novartis. P. Ernst has received speaker's fees from or served on an advisory board for AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Merck, Novartis, and Nycomed. Q. Hamid has received research support from the McGill University Health Center Strauss Foundation. The rest of the authors have declared that they have no conflict of interest.

    PII: S0091-6749(09)00637-X

    doi:10.1016/j.jaci.2009.03.049

    The Journal of Allergy and Clinical Immunology
    Volume 124, Issue 1 , Pages 45-51.e4, July 2009