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The Journal of Allergy and Clinical Immunology
Volume 123, Issue 6
, Pages 1253-1259.e2
, June 2009
Higher serum folate levels are associated with a lower risk of atopy and wheeze
References
- . Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study. N Engl J Med. 1990;323:502–507
- The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. N Engl J Med. 1997;336:1356–1363
- Household mouse allergen exposure and asthma morbidity in inner-city pre-school children. Ann Allergy Asthma Immunol. 2006;97:514–520
- . The role of indoor allergen sensitization and exposure in causing morbidity in women with asthma. Am J Respir Crit Care Med. 2002;165:961–966
- Sensitization to dust mites as a dominant risk factor for asthma among adolescents living in central Virginia. Multiple regression analysis of a population-based study. Am J Respir Crit Care Med. 1997;156:1760–1764
- . Effect of cat and dog ownership on sensitization and development of asthma among preteenage children. Am J Respir Crit Care Med. 2002;166:696–702
- Results of a home-based environmental intervention among urban children with asthma. N Engl J Med. 2004;351:1068–1080
- . Health effects of indoor nitrogen dioxide and passive smoking on urban asthmatic children. J Allergy Clin Immunol. 2007;120:618–624
- Home environmental intervention in inner-city asthma: a randomized controlled clinical trial. Ann Allergy Asthma Immunol. 2005;95:518–524
- Ambient ozone concentrations cause increased hospitalizations for asthma in children: an 18-year study in Southern California. Environ Health Perspect. 2008;116:1063–1070
- . Air pollution and pulmonary function in asthmatic children: effects of prenatal and lifetime exposures. Epidemiology. 2008;19:550–557
- A longitudinal study of indoor nitrogen dioxide levels and respiratory symptoms in inner-city children with asthma. Environ Health Perspect. 2008;116:1428–1432
- . Endotoxin exposure is a risk factor for asthma: the national survey of endotoxin in United States housing. Am J Respir Crit Care Med. 2005;172:1371–1377
- Endotoxin in inner-city homes: associations with wheeze and eczema in early childhood. J Allergy Clin Immunol. 2006;117:1082–1089
- Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med. 2002;347:869–877
- . Timing of routine vaccinations and the risk of childhood asthma. J Allergy Clin Immunol. 2008;122:656–658
- . Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma. J Allergy Clin Immunol. 2008;121:626–631
- . Absence of relationships between tuberculin responses and development of adult asthma with rhinitis and atopy. Chest. 2008;133:100–106
- Is the prevalence of wheeze in children altered by neonatal BCG vaccination?. J Allergy Clin Immunol. 2007;119:1079–1085
- . Mediterranean diet as a protective factor for wheezing in preschool children. J Pediatr. 2008;152:823–828
- Maternal food consumption during pregnancy and the longitudinal development of childhood asthma. Am J Respir Crit Care Med. 2008;178:124–131
- Low dietary nutrient intakes and respiratory health in adolescents. Chest. 2007;132:238–245
- Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr. 2007;85:788–795
- . Asthma and current intestinal parasite infection: systematic review and meta-analysis. Am J Respir Crit Care Med. 2006;174:514–523
- Wheezing, allergy, and parasite infection in children in urban and rural Ethiopia. Am J Respir Crit Care Med. 2003;167:1369–1373
- Independent effects of intestinal parasite infection and domestic allergen exposure on risk of wheeze in Ethiopia: a nested case-control study. Lancet. 2001;358:1493–1499
- Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children. Am J Respir Crit Care Med. 2008;178:667–672
- . The September epidemic of asthma hospitalization: school children as disease vectors. J Allergy Clin Immunol. 2006;117:557–562
- Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma. J Allergy Clin Immunol. 2007;119:1105–1110
- In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest. 2008;118:3462–3469
- . Temporal trends of aeroallergen sensitization over twenty-five years. Clin Exp Allergy. 2007;37:1137–1142
- . Surveillance for asthma—United States, 1980-1999. MMWR Surveill Summ. 2002;51:1–13
- Blood folate levels: the latest NHANES results. Hyattsville (MD): National Center for Health Statistics; 2008;NCHS data briefs no. 6
- Effect of folic acid on endothelial function following acute myocardial infarction. Am J Cardiol. 2007;99:476–481
- . Folate intake and the risk of incident hypertension among US women. JAMA. 2005;293:320–329
- . Diets lower in folic acid and carotenoids are associated with the coronary disease epidemic in Central and Eastern Europe. J Am Diet Assoc. 2004;104:1793–1799
- . MTHFR 677C→T polymorphism and risk of coronary heart disease: a meta-analysis. JAMA. 2002;288:2023–2031
- Moderate hyperhomocysteinaemia and immune activation in patients with rheumatoid arthritis. Clin Chim Acta. 2003;338:157–164
- . 677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis. Pharmacogenomics. 2007;8:1551–1559
- Centers for Disease Control and Prevention, National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey data. Available at: www.cdc.gov/nchs/about/major/nhanes/nhanes2005-6/nhanes05_06.htm. Accessed 2008.
- . The association between atopy and factors influencing folate metabolism: is low folate status causally related to the development of atopy?. Int J Epidemiol. 2006;35:954–961
- A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci U S A. 2002;99:5606–5611
- . The association between mother and child MTHFR C677T polymorphisms, dietary folate intake and childhood atopy in a population-based, longitudinal birth cohort. Clin Exp Allergy. 2008;38:320–328
- . Contributions of total daily intake of folic acid to serum folate concentrations. JAMA. 2008;300:2486–2487
- . The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B12 status. Food Nutr Bull. 2008;29(suppl):S67–S73
- . Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr. 2007;85:193–200
- . Prevalences of positive skin test responses to 10 common allergens in the US population: results from the third National Health and Nutrition Examination Survey. J Allergy Clin Immunol. 2005;116:377–383
- . Folic acid supplements in pregnancy and early childhood respiratory health. Arch Dis Child. 2009;94:180–184
- . Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects. Int J Obes (Lond). 2006;30:1197–1202
- . Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process. Nat Immunol. 2003;4:235–240
- . DNA methylation and human disease. Nat Rev Genet. 2005;6:597–610
- Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors. Arthritis Rheum. 2004;50:1850–1860
- . Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. J Immunol. 2005;174:6212–6219
- . Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues. Biochem Biophys Res Commun. 2008;373:151–154
- A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-kappaB and hypoxia-inducible factor-1alpha. Exp Mol Med. 2007;39:756–768
- Homocysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med. 2006;354:1578–1588
Supported by grants from the National Institute of Allergy and Infectious Diseases (R01AI070630) and the National Institutes of Environmental Health Sciences (DISCOVER Award 5P50ES015903).
Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.
PII: S0091-6749(09)00387-X
doi: 10.1016/j.jaci.2009.03.007
© 2009 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
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The Journal of Allergy and Clinical Immunology
Volume 123, Issue 6
, Pages 1253-1259.e2
, June 2009
