The Journal of Allergy and Clinical Immunology
Volume 123, Issue 6 , Pages 1253-1259.e2 , June 2009

Higher serum folate levels are associated with a lower risk of atopy and wheeze

  • Elizabeth C. Matsui, MD, MHS

      Affiliations

    • Division of Pediatric Allergy and Immunology, Johns Hopkins School of Medicine, Baltimore, Md
    • Corresponding Author InformationReprint requests: Elizabeth C. Matsui, MD, MHS, The Johns Hopkins Hospital, CMSC 1102, 600 N Wolfe St, Baltimore, MD 21287.
  • ,
  • William Matsui, MD

      Affiliations

    • Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Md

Received 9 November 2008 ,Revised 27 February 2009 ,Accepted 3 March 2009.

  • Image Result

    Distribution of serum total IgE levels across quintiles of serum folate. Outside values are not shown. Geometric mean total IgE levels for each quintile of serum folate are as follows: 53.6, 44.9, 45.

    Distribution of serum total IgE levels across quintiles of serum folate. Outside values are not shown. Geometric mean total IgE levels for each quintile of serum folate are as follows: 53.6, 44.9, 45.1, 38.7, and 34.5 kU/L, respectively. P < .001 for trend.

 Supported by grants from the National Institute of Allergy and Infectious Diseases (R01AI070630) and the National Institutes of Environmental Health Sciences (DISCOVER Award 5P50ES015903).

 Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.

PII: S0091-6749(09)00387-X

doi: 10.1016/j.jaci.2009.03.007

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 6 , Pages 1253-1259.e2 , June 2009