The Journal of Allergy and Clinical Immunology
Volume 123, Issue 4 , Pages 875-882.e1 , April 2009

Toll-like receptor 2 is important for the TH1 response to cutaneous sensitization

  • Haoli Jin, MD, PhD

      Affiliations

    • Division of Immunology, Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, Mass
    • These authors contributed equally to this work.
    • ,
  • Lalit Kumar, PhD

      Affiliations

    • Division of Immunology, Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, Mass
    • These authors contributed equally to this work.
    • ,
  • Clinton Mathias, PhD

      Affiliations

    • Division of Immunology, Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, Mass
    • ,
  • David Zurakowski, PhD

      Affiliations

    • Department of Anesthesia and Surgery, Children's Hospital, Boston, Mass
    • ,
  • Hans Oettgen, MD, PhD

      Affiliations

    • Division of Immunology, Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, Mass
    • ,
  • Leonid Gorelik, PhD

      Affiliations

    • Biogen Idec, Inc, Cambridge, Mass
    • ,
  • Raif Geha, MD

      Affiliations

    • Division of Immunology, Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, Mass
    • Corresponding Author InformationReprint requests: Raif Geha, MD, Division of Immunology, Room 10210, Karp Family Research Building, Children's Hospital, One Blackfan Circle, Boston, MA 02115.

Received 20 August 2008 ,Revised 22 January 2009 ,Accepted 4 February 2009.

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 Supported by the Atopic Dermatitis and Vaccinia Immunization Network; National Institutes of Health/National Institute of Allergy and Infectious Diseases contract NO1 (AI 40030); and a US Public Health Service grant AR-047417 to R.G. H.J. has received a postdoctoral fellowship from the American Heart Association.

 Disclosure of potential conflict of interest: H. Jin has received research support from the American Heart Association. H. Oettgen has served as a consultant and scientific advisor for Schering-Plough and as a consultant for Genentech and has received research support from Novartis. L. Gorelik is employed by Biogen Idec, Inc. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(09)00233-4

doi: 10.1016/j.jaci.2009.02.007

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 4 , Pages 875-882.e1 , April 2009

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