The Journal of Allergy and Clinical Immunology
Volume 123, Issue 5 , Pages 1163-1169.e4 , May 2009

Association of obesity with IgE levels and allergy symptoms in children and adolescents: Results from the National Health and Nutrition Examination Survey 2005-2006

  • Cynthia M. Visness, PhD

      Affiliations

    • Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
    • Rho Federal Systems Division, Inc, Chapel Hill, NC
    • Corresponding Author InformationReprint requests: Cynthia M. Visness, PhD, Rho Federal Systems Division, Inc, 6330 Quadrangle Dr, Suite 500, Chapel Hill, NC 27517.
    • ,
  • Stephanie J. London, MD, DrPH

      Affiliations

    • Division of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC
    • ,
  • Julie L. Daniels, PhD

      Affiliations

    • Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
    • ,
  • Jay S. Kaufman, PhD

      Affiliations

    • Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
    • ,
  • Karin B. Yeatts, PhD

      Affiliations

    • Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
    • ,
  • Anna-Maria Siega-Riz, PhD

      Affiliations

    • Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
    • ,
  • Andrew H. Liu, MD

      Affiliations

    • National Jewish Health and University of Colorado Health Science Center, Denver, Colo
    • ,
  • Agustin Calatroni, MA, MS

      Affiliations

    • Rho Federal Systems Division, Inc, Chapel Hill, NC
    • ,
  • Darryl C. Zeldin, MD

      Affiliations

    • Division of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC

Received 3 December 2008 ,Accepted 19 December 2008.

  • Image Result

    Association between BMI percentile for age and total IgE level by sex, NHANES 2005-2006, children age 2 to 19 years. The shaded region represents the 95% confidence limits of the data. The black lines

    Association between BMI percentile for age and total IgE level by sex, NHANES 2005-2006, children age 2 to 19 years. The shaded region represents the 95% confidence limits of the data. The black lines represent observations and show where the data lie on the BMI distribution. The x-axis is plotted as the z score for BMI for age and labeled with the transformation of z scores to percentiles.

  • Image Result
    Prevalence of atopy by race and weight status among girls, NHANES 2005-2006, children age 2 to 19 years. The dots reflect the mean prevalence of atopy, and the bars represent the 95% CI.

    Prevalence of atopy by race and weight status among girls, NHANES 2005-2006, children age 2 to 19 years. The dots reflect the mean prevalence of atopy, and the bars represent the 95% CI.

  • Image Result
    Correlation between percentage body fat measured by means of DXA and BMI z score by age group (in quintiles), sex, and race/ethnicity in unweighted data from NHANES 1999-2004. The dark gray line repre

    Correlation between percentage body fat measured by means of DXA and BMI z score by age group (in quintiles), sex, and race/ethnicity in unweighted data from NHANES 1999-2004. The dark gray line represents the median BMI, and the light gray lines represent the 85th and 95th percentiles of BMI for age and sex. The correlation (with 95% CI) is given overall and above and below the median value for each age/sex group.

 Supported in part by the Intramural Research Program of the National Institutes of Health, National Institute of Environmental Health Sciences (Z01 ES025041-10), and by the National Institute of Allergy and Infectious Diseases, National Institutes of Health (NO1-AI-25482).

 Disclosure of potential conflict of interest: J. S. Kaufman receives grant support from the Robert Wood Johnson Foundation and the National Institutes of Health. A.-M. Siega-Riz receives grant support from the National Institute of Diabetes and Digestive and Kidney Diseases, the Centers for Disease Control and Prevention, the National Institutes of Health, and the National Heart, Lung, and Blood Institute; is on the advisory board for the American Diabetes Association; and is a scientific advisor for Nestle-Gerber products and Shoulder to Shoulder. A. H. Liu is on the review board for the National Institutes of Health/National Institute of Environmental Health Sciences. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(09)00115-8

doi: 10.1016/j.jaci.2008.12.1126

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 5 , Pages 1163-1169.e4 , May 2009

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