The Journal of Allergy and Clinical Immunology
Volume 123, Issue 2 , Pages 309-316.e4, February 2009

Complementary and alternative medicine for the allergist-immunologist: Where do I start?

  • Renata J.M. Engler, MD, FAAAAI, FACAAI

      Affiliations

    • Vaccine Healthcare Centers Network, Allergy-Immunology Department, Walter Reed Army Medical Center, Washington, DC
    • Medicine and Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Md
    • Corresponding Author InformationReprint requests: Renata J. M. Engler, MD, FAAAAI, FACAAI, Director, Vaccine Healthcare Centers Network, Allergy-Immunology Department, Walter Reed Army Medical Center, Washington, DC 20307-5001.
  • ,
  • Catherine M. With, JD, LLM, LLM

      Affiliations

    • Armed Forces Institute of Pathology, Washington, DC
  • ,
  • Philip J. Gregory, PharmD

      Affiliations

    • Natural Medicines Comprehensive Database, Stockton, Calif
    • Center for Drug Information and Evidence-Based Practice, Creighton University, Omaha, Neb
  • ,
  • Jeff M. Jellin, PharmD

      Affiliations

    • Natural Medicines Comprehensive Database, Stockton, Calif
    • Pharmacist's Letter and Prescriber's Letter, Stockton, Calif

Received 6 November 2008; received in revised form 24 December 2008; accepted 5 January 2009.

Complementary and alternative medicine (CAM) therapies present a growing information management challenge for physicians because nearly 40% of their patients may be using and another 50% may be considering use of CAM as part of their healthcare regimen. The National Health Statistics Reports for 2007 described the most commonly used nonvitamin, nonmineral therapy as natural products (eg, herbals at 17.7%). More than 5% of children under the age of 18 years used CAM for allergic conditions including asthma. The amount and quality of information available and concerns about liability risk represent a challenge for most physicians. This review focuses on considerations for approaching a CAM-related consultation, incorporating legal and logistic factors affecting how such an encounter should be approached. A 10-step process is presented that addresses different components of CAM consultations and what should be documented. Access to timely, high-quality information regarding product specific efficacy and safety data, as found in the Natural Medicines Comprehensive Database, is needed to support CAM consultation efficiently. Understanding of serious adverse events associated with CAM is limited; an international need exists for improved safety surveillance and information sharing. Allergy-immunology, as a specialty with expertise in adverse drug reaction evaluation and management, has a unique opportunity to support enhanced CAM-related adverse events evaluations, reporting, and research.

Key words: Complementary and alternative medicine, integrative medicine, herbals, herbs, adverse reactions, risk communication, quality of care

Abbreviations used: CAM, Complementary and alternative medicine, FDA, Food and Drug Administration, NCCAM, National Center for Complementary and Alternative Medicine, NIH, National Institutes of Health

 

 The views expressed in this article are those of the authors and do not reflect the official policy of the Department of Army, Department of Defense, United States Government, or other federal agencies.

 Disclosure of potential conflict of interest: J. M. Jellin is president of the Therapeutic Research Center. P. J. Gregory is a consultant for the Therapeutic Research Center and has provided legal consultation or expert witness testimony on the topic of chelation therapy. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(09)00004-9

doi:10.1016/j.jaci.2009.01.001

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 2 , Pages 309-316.e4, February 2009