The Journal of Allergy and Clinical Immunology
Volume 123, Issue 3 , Pages 665-671.e6 , March 2009

Quantitative assessment of allergic shiners in children with allergic rhinitis

  • Chien-Han Chen, MD

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Department of Pediatrics, Min-Sheng General Hospital, Taoyuan, Taiwan
  • ,
  • Yu-Tsan Lin, MD, PhD

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Che-Yen Wen, PhD

      Affiliations

    • Department of Forensic Science, National Central Police University, Taoyuan, Taiwan
  • ,
  • Li-Chieh Wang, MD

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Kuo-Hung Lin, MS

      Affiliations

    • Department of Polymer Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan
  • ,
  • Shih-Hsuan Chiu, PhD

      Affiliations

    • Department of Polymer Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan
  • ,
  • Yao-Hsu Yang, MD, PhD

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Jyh-Hong Lee, MD

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
  • ,
  • Bor-Luen Chiang, MD, PhD

      Affiliations

    • Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    • Corresponding Author InformationReprint requests: Bor-Luen Chiang, MD, PhD, Department of Pediatrics, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei 100, Taiwan, Republic of China.

Received 10 June 2008 ,Revised 9 December 2008 ,Accepted 15 December 2008.

  • Image Result

    Measurement of darkness of shiners. Darkness of shiners was measured by using the semiautomatic method (A and B) and the manual method (C and D). The gray-level mean values in the infraorbital groove

    Measurement of darkness of shiners. Darkness of shiners was measured by using the semiautomatic method (A and B) and the manual method (C and D). The gray-level mean values in the infraorbital groove and cheek were computed in the upper and lower slanted triangle regions, respectively, in both of the 2 methods.

  • Image Result
    Eyelid sampling and measurement of area values of shiners. The lower eyelid curve (A) was sketched with automatic downward extension of 242 pixels from the lowest point of the red curve to mark a boun

    Eyelid sampling and measurement of area values of shiners. The lower eyelid curve (A) was sketched with automatic downward extension of 242 pixels from the lowest point of the red curve to mark a boundary. This region was examined with the entropy theorem, and a line of demarcation was plotted automatically to circumscribe the area of shiners (B).

  • Image Result
    The effect of allergic rhinitis on the formation of allergic shiners. A, Dave, Average of darkness of shiners on the left and right sides. B, Aave, average of area values of body surface area on the l

    The effect of allergic rhinitis on the formation of allergic shiners. A, Dave, Average of darkness of shiners on the left and right sides. B, Aave, average of area values of body surface area on the left and right sides.

  • Image Result
    The thresholds of symptoms associated with enhanced darkness (A, B, E, and F) or increased sizes (C and D) of shiners on different visits. Dave, Average of darkness of shiners on the left and right si

    The thresholds of symptoms associated with enhanced darkness (A, B, E, and F) or increased sizes (C and D) of shiners on different visits. Dave, Average of darkness of shiners on the left and right sides; Aave, average of area values of body surface area on the left and right sides; SGAE1d, SGAE recorded on the day before visits; SGAE1wk, SGAE summed from daily scores in the past week.

  • Image Result
    The position of the color checker.

    The position of the color checker.

  • Image Result
    Correlations of shiners between 2 sides (A, B, and D) and between the semiautomatic and manual methods (C). DL, Darkness of shiners on the left side; DR, darkness of shiners on the right side; Dave, a

    Correlations of shiners between 2 sides (A, B, and D) and between the semiautomatic and manual methods (C). DL, Darkness of shiners on the left side; DR, darkness of shiners on the right side; Dave, average of darkness of shiners on the left and right sides; AL, area value of shiners normalized by body surface area on the left side; AR, area value of shiners normalized by body surface area on the right side.

  • Image Result
    Reliabilities for measurement of darkness by using the semiautomatic method (A) and for measurement of area values (B) of shiners. Test 2 performed on the same digital photographs was carried out 2 ye

    Reliabilities for measurement of darkness by using the semiautomatic method (A) and for measurement of area values (B) of shiners. Test 2 performed on the same digital photographs was carried out 2 years after test 1. Dave, Average of darkness of shiners on the left and right sides; ICC, intraclass correlation coefficient; Aave, average of area values of body surface area on the left and right sides.

  • Image Result
    A and B, The thresholds between the control and allergic rhinitis groups at the first visit. PDF, Frequency count/numbers of all samples; AR, allergic rhinitis; NC, normal control.

    A and B, The thresholds between the control and allergic rhinitis groups at the first visit. PDF, Frequency count/numbers of all samples; AR, allergic rhinitis; NC, normal control.

 Supported by a grant from National Taiwan University Hospital.

 Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.

PII: S0091-6749(08)03476-3

doi: 10.1016/j.jaci.2008.12.1108

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 3 , Pages 665-671.e6 , March 2009