The Journal of Allergy and Clinical Immunology
Volume 123, Issue 2 , Pages 504-505 , February 2009

Successful treatment of chronic drug-resistant urticaria with alprazolam

  • Antonio Dueñas-Laita, MD, PhD

      Affiliations

    • Servicio de Farmacología Clínica–Unidad Regional de Toxicología Clínica, Hospital Universitario Río Hortega, Valladolid, Spain
    • ,
  • Pedro Ruiz-Muñoz, MD

      Affiliations

    • Asociación Castellano Leonesa de Ayuda a Drogodependientes, Valladolid, Spain
    • ,
  • Alicia Armentia, MD, PhD

      Affiliations

    • Sección de Alergia, Hospital Universitario Río Hortega, Valladolid, Spain
    • ,
  • Florentino Pinacho, DUE

      Affiliations

    • Servicio de Farmacología Clínica–Unidad Regional de Toxicología Clínica, Hospital Universitario Río Hortega, Valladolid, Spain
    • ,
  • Blanca Martín-Armentia, PhT

      Affiliations

    • Servicio de Farmacología Clínica–Unidad Regional de Toxicología Clínica, Hospital Universitario Río Hortega, Valladolid, Spain

References 

  1. Alvarez FJ, Velasco A, Palomares JL. Blockade of muscarinic, histamine H1 and Histamine H2 receptors by antidepressants. Pharmacology. 1988;37:225–231
  2. Darius H, Smith JB, Lefer AM. Inhibition of the platelet activating factor mediated component of guinea pig anaphylaxis by receptor antagonists. Int Arch Allergy Appl Immunol. 1986;80:369–375
  3. De Vance Cl, Hill M, Antal EJ. Therapeutic drug monitoring of alprazolam in adolescents with asthma. Ther Drug Monit. 1998;20:257–260
  4. Sellas-Dupre G, Nieto Lopez M, Garcia Vicente JA, Salvador–Chiva J. Alprazolam-induced tongue angioedema. Pharmacopsychiatry. 2006;39:154–156
  5. Hide M, Francis DM, Gratton CE, Hakimi J, Kochan JP, Greaves MW. Autoantibodies against the high affinity IgE receptor as a cause of histamine release in chronic urticaria. N Engl J Med. 1993;328:1599–1604
  6. Deacock SJ. An approach to the patient with urticaria. Clin Exp Immunol. 2008;153:151–161
  7. Morel V, Hauser C. Chronic urticaria. Rev Med Suisse. 2008;4:1019–1023
  8. Kaplan AP. Chronic urticaria: pathogenesis and treatment. J Allergy Clin Immunol. 2004;114:465–474
  9. Serhat Inaloz H, Ozturk S, Akcali C, Kirtak N, Tarakcioglu M. Low-dose and short-term cyclosporine treatment in patients with chronic idiopathic urticaria: a clinical and immunological evaluation. Dermatology. 2008;35:276–282
  10. Pereira C, Tavares B, Carrapatoso I, Loureiro G, Faria E, Machado D, et al. Low-dose intravenous gammaglobulin in the treatment of severe autoimmune urticaria. Eur Ann Allergy Clin Immunol. 2007;39:237–242
  11. Spector SL, Tan RA. Omalizumab also successful in chronic urticaria. J Allergy Clin Immunol. 2008;121:784–785

 Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.

PII: S0091-6749(08)02355-5

doi: 10.1016/j.jaci.2008.12.005

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 2 , Pages 504-505 , February 2009

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