The Journal of Allergy and Clinical Immunology
Volume 123, Issue 2 , Pages 391-397 , February 2009

Oral contraception, body mass index, and asthma: A cross-sectional Nordic-Baltic population survey

  • Ferenc Macsali, MD

      Affiliations

    • Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway
    • Bergen Respiratory Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    • Corresponding Author InformationReprint requests: Ferenc Macsali, MD, Department of Gynecology and Obstetrics, Haukeland University Hospital, 5021 Bergen, Norway.
  • ,
  • Francisco Gómez Real, MD, PhD

      Affiliations

    • Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway
    • Bergen Respiratory Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
  • ,
  • Ernst Reidar Omenaas, MD, PhD

      Affiliations

    • Center for Clinical Research, Haukeland University Hospital, Bergen, Norway
    • Bergen Respiratory Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
  • ,
  • Line Bjorge, MD, PhD

      Affiliations

    • Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway
  • ,
  • Christer Janson, MD, PhD

      Affiliations

    • Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
  • ,
  • Karl Franklin, MD, PhD

      Affiliations

    • Department of Respiratory Medicine, University Hospital, Umeå, Sweden
  • ,
  • Cecilie Svanes, MD, PhD

      Affiliations

    • Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway
    • Bergen Respiratory Research Group, Institute of Medicine, University of Bergen, Bergen, Norway

Received 23 May 2008 ,Revised 21 October 2008 ,Accepted 27 October 2008.

  • Image Result

    Meta-analysis of the association of oral contraceptive (OC) pills with asthma (A) and ≥3 asthma symptoms (B) by center. The size of the squares is proportional with the study sample from each center.

    Meta-analysis of the association of oral contraceptive (OC) pills with asthma (A) and ≥3 asthma symptoms (B) by center. The size of the squares is proportional with the study sample from each center. The horizontal lines show the 95% CIs. The diamond shows the combined OR with 95% CI.

  • Image Result
    Generalized additive model curves showing prevalence (proportion) of asthma (A) and ≥3 asthma symptoms (B) according to BMI with or without oral contraceptives (OC).

    Generalized additive model curves showing prevalence (proportion) of asthma (A) and ≥3 asthma symptoms (B) according to BMI with or without oral contraceptives (OC).

 Supported by the Icelandic Research Council, the Swedish Heart and Lung Foundation, the Vårdal Foundation for Health Care Science and Allergy Research, the Swedish Association Against Asthma and Allergy, the Norwegian Research Council project 135773/330, the Norwegian Asthma and Allergy Association, the Danish Lung Association, and the Estonian Science Foundation grant no. 4350. F.M. was supported by a grant from the Regional Health Authority of Western Norway and from the Norwegian Foundation for Health and Rehabilitation.

 Disclosure of potential conflict of interest: K. Franklin receives grant support from the Swedish Heart and Lung Foundation. L. Bjorge is a member of the Norwegian Cancer Society, the Amathea Foundation in Hordaland, and the Norwegian Society for Obstetrics and Gynecology. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(08)01917-9

doi: 10.1016/j.jaci.2008.10.041

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 2 , Pages 391-397 , February 2009