The Journal of Allergy and Clinical Immunology
Volume 123, Issue 3 , Pages 632-638 , March 2009

Increased asthma and respiratory symptoms in children exposed to petrochemical pollution

  • Fernando A. Wichmann, MD

      Affiliations

    • Instituto del Desarrollo de Investigaciones Pediátricas (IDIP) Prof Dr Fernando Viteri Hospital de Niños SM Ludovica, La Plata, Argentina
    • Corresponding Author InformationReprint requests: Fernando A. Wichmann, MD, Instituto de Investigaciones Pediátricas, (IDIP) Hospital de Niños SM Ludoviva, La Plata, Argentina.
    • ,
  • Andrea Müller

      Affiliations

    • Department of Human Exposure Research and Epidemiology, Heimholtz-Zentrum für Umweltforschung GmbH–UFZ, Leipzig-Halle, Germany
    • ,
  • Luciano E. Busi

      Affiliations

    • Instituto del Desarrollo de Investigaciones Pediátricas (IDIP) Prof Dr Fernando Viteri Hospital de Niños SM Ludovica, La Plata, Argentina
    • ,
  • Natalia Cianni

      Affiliations

    • Centro de Investigaciones del Medio Ambiente (CIMA) Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina
    • ,
  • Laura Massolo

      Affiliations

    • Centro de Investigaciones del Medio Ambiente (CIMA) Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina
    • ,
  • Uwe Schlink

      Affiliations

    • Department of Human Exposure Research and Epidemiology, Heimholtz-Zentrum für Umweltforschung GmbH–UFZ, Leipzig-Halle, Germany
    • ,
  • Andres Porta, PhD

      Affiliations

    • Centro de Investigaciones del Medio Ambiente (CIMA) Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina
    • ,
  • Peter David Sly, MBBS, MD, DSc, FRACP

      Affiliations

    • World Health Organization Collaborating Centre for Research on Children's Environmental Health, Telethon Institute for Child Health Research and School of Public Health, Curtin University for Technology, Perth, Australia

Received 26 November 2007 ,Revised 25 September 2008 ,Accepted 29 September 2008.

  • Image Result

    Study locations in La Plata, Argentina. The petrochemical industry (industrial [I]) is located to the northeast of the main city region (urban [U]). Two relatively nonpolluted areas, semirural (SR) an

    Study locations in La Plata, Argentina. The petrochemical industry (industrial [I]) is located to the northeast of the main city region (urban [U]). Two relatively nonpolluted areas, semirural (SR) and residential (R), are also shown. The shaded regions show where municipal pollution-monitoring stations were located.

  • Image Result
    Lung function, expressed as FEV1 (percent predicted) in children living in the different geographic regions. Box plots show the median and interquartile ranges, with outliers shown as symbols.

    Lung function, expressed as FEV1 (percent predicted) in children living in the different geographic regions. Box plots show the median and interquartile ranges, with outliers shown as symbols.

 The Scientific Research Commission of the Province of Buenos Aires (CIC-PBA) and the National University of La Plata financed the present study.

 Disclosure of potential conflict of interest: N. Cianni and A. Porta have received research support from the Comision de Investigaciones Cientificas de la Provincia de Buenos Aires and from Universidad Nacional de la Plata (Argentina). The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(08)01879-4

doi: 10.1016/j.jaci.2008.09.052

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 3 , Pages 632-638 , March 2009

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