The Journal of Allergy and Clinical Immunology
Volume 123, Issue 1 , Pages 231-238.e4 , January 2009

Impairing oral tolerance promotes allergy and anaphylaxis: A new murine food allergy model

  • Kirthana Ganeshan, BS

      Affiliations

    • Division of Allergy-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Ill
    • These authors contributed equally to this work.
  • ,
  • Colleen V. Neilsen, BS

      Affiliations

    • Division of Allergy-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Ill
    • These authors contributed equally to this work.
  • ,
  • April Hadsaitong, MD

      Affiliations

    • Division of Allergy-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Ill
  • ,
  • Robert P. Schleimer, PhD

      Affiliations

    • Division of Allergy-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Ill
  • ,
  • Xunrong Luo, MD, PhD

      Affiliations

    • Division of Nephrology-Hypertension, Feinberg School of Medicine, Northwestern University, Chicago, Ill
  • ,
  • Paul J. Bryce, PhD

      Affiliations

    • Division of Allergy-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Ill
    • Corresponding Author InformationReprint requests: Paul Bryce, PhD, Division of Allergy-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60610.

Received 17 July 2008 ,Revised 26 September 2008 ,Accepted 6 October 2008.

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 Supported by the Food Allergy Project. R.P.S. was supported by National Institutes of Health (NIH) grants RO1 HL068546, HL078860, and AI072570. P.J.B. was supported by NIH grants RO1 AI076456 and R21 AI078525.

 Disclosure of potential conflict of interest: X. Luo has received research support from the National Institutes of Health and the Juvenile Diabetes Research Foundation. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(08)01854-X

doi: 10.1016/j.jaci.2008.10.011

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 1 , Pages 231-238.e4 , January 2009