The Journal of Allergy and Clinical Immunology
Volume 123, Issue 1 , Pages 53-58 , January 2009

Targeting IL-4/IL-13 signaling to alleviate oral allergen–induced diarrhea

  • Eric B. Brandt, PhD

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • ,
  • Ariel Munitz, PhD

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • ,
  • Tatyana Orekov, MS

      Affiliations

    • Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • ,
  • Melissa K. Mingler, MS

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • ,
  • Melissa McBride, BS

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • ,
  • Fred D. Finkelman, MD

      Affiliations

    • Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • Division of Immunology, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Marc E. Rothenberg, MD, PhD

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    • Corresponding Author InformationReprint requests: Marc E. Rothenberg, MD, PhD, Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229.

Received 5 August 2008 ,Revised 7 September 2008 ,Accepted 1 October 2008.

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 Supported in part by National Institutes of Health grant AI45898-05, the Campaign Urging Research for Eosinophilic Diseases (CURED), the Food Allergy Project, and the US Department of Veterans Affairs.

 Disclosure of potential conflict of interest: F. D. Finkelman has served as a consultant for Amgen and Abbott. M. E. Rothenberg has served as a speaker and consultant for Merck and as a consultant for Ception Therapeutics, Novartis, and Nycomed and has received research support from the National Institutes of Health, the Food Allergy and Anaphylaxis Network, and the Dana Foundation. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(08)01742-9

doi: 10.1016/j.jaci.2008.10.001

The Journal of Allergy and Clinical Immunology
Volume 123, Issue 1 , Pages 53-58 , January 2009

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