The Journal of Allergy and Clinical Immunology
Volume 122, Issue 5 , Pages 914-920 , November 2008

Anti-cockroach and anti-mouse IgE are associated with early wheeze and atopy in an inner-city birth cohort

  • Kathleen M. Donohue, MD

      Affiliations

    • Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY
  • ,
  • Umaima Al-alem, PhD

      Affiliations

    • Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Ill
  • ,
  • Matthew S. Perzanowski, PhD

      Affiliations

    • Columbia Center for Children's Environmental Health (CCCEH), Columbia University, New York, NY
    • Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY
  • ,
  • Ginger L. Chew, ScD

      Affiliations

    • Columbia Center for Children's Environmental Health (CCCEH), Columbia University, New York, NY
    • Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY
  • ,
  • Alina Johnson, BA

      Affiliations

    • Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY
    • Columbia Center for Children's Environmental Health (CCCEH), Columbia University, New York, NY
  • ,
  • Adnan Divjan

      Affiliations

    • Columbia Center for Children's Environmental Health (CCCEH), Columbia University, New York, NY
    • Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY
  • ,
  • Elizabeth A. Kelvin, PhD

      Affiliations

    • Data Coordinating Center at New York State Psychiatric Institute and Columbia University, New York, NY
  • ,
  • Lori A. Hoepner, MPH

      Affiliations

    • Columbia Center for Children's Environmental Health (CCCEH), Columbia University, New York, NY
    • Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY
  • ,
  • Frederica P. Perera, DrPH

      Affiliations

    • Columbia Center for Children's Environmental Health (CCCEH), Columbia University, New York, NY
    • Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY
  • ,
  • Rachel L. Miller, MD

      Affiliations

    • Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY
    • Columbia Center for Children's Environmental Health (CCCEH), Columbia University, New York, NY
    • Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY
    • Corresponding Author InformationReprint requests: Rachel L. Miller, MD, Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, 622 West 168th St, PH 8 E 101, New York, NY 10032.

Received 25 April 2008 ,Revised 23 July 2008 ,Accepted 14 August 2008.

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 Supported by the National Institute of Environmental Health Sciences (grant nos. 5 P01 ES009600, 5 R01 ES008977, and P30 ES009089), the US Environmental Protection Agency (grant nos. R827027 and RD-832141), the Irving General Clinical Research Center (grant no. RR00645), the Educational Foundation of America, the Horace W. Goldsmith Foundation, the Gladys & Roland Harriman Foundation, The John Merck Fund, The New York Community Trust, and the Trustees of the Blanchette Hooker Rockefeller Fund.

 Disclosure of potential conflict of interest: M. S. Perzanowski has received grant from the National Institutes of Health (NIH). G. L. Chew has received grants from the National Institute of Environmental Health Sciences. R. L. Miller has received grants or other research funding from the NIH, the Environmental Protection Agency, and the Sandler Program for Asthma Research. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(08)01667-9

doi: 10.1016/j.jaci.2008.08.034

The Journal of Allergy and Clinical Immunology
Volume 122, Issue 5 , Pages 914-920 , November 2008