The Journal of Allergy and Clinical Immunology
Volume 122, Issue 6 , Pages 1169-1177.e16 , December 2008

Hypomorphic nuclear factor-κB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity

  • Eric P. Hanson, MD

      Affiliations

    • Division of Rheumatology, Joseph Stokes Jr Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pa
    • ,
  • Linda Monaco-Shawver, BA

      Affiliations

    • Division of Allergy and Immunology, Joseph Stokes Jr Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pa
    • ,
  • Laura A. Solt, BS

      Affiliations

    • Department of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pa
    • ,
  • Lisa A. Madge, PhD

      Affiliations

    • Department of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pa
    • ,
  • Pinaki P. Banerjee, PhD

      Affiliations

    • Division of Allergy and Immunology, Joseph Stokes Jr Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pa
    • ,
  • Michael J. May, PhD

      Affiliations

    • Department of Animal Biology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pa
    • ,
  • Jordan S. Orange, MD, PhD

      Affiliations

    • Division of Allergy and Immunology, Joseph Stokes Jr Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pa
    • Corresponding Author InformationReprint requests: Jordan S. Orange, MD, PhD, Children's Hospital of Philadelphia, Abramson Research Center 1016H, 3615 Civic Center Boulevard, Philadelphia, PA 19104.

Received 30 June 2008 ,Revised 18 August 2008 ,Accepted 20 August 2008.

References 

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 Supported by National Institutes of Health (NIH) AI079731 (J.S.O.), US Immunodeficiency Network Grant NIH N01 AI-22070 (J.S.O., M.J.M.), NIH HL080612 (M.J.M), the Pennsylvania Department of Health (J.S.O.; the Pennsylvania Department of Health specifically disclaims responsibility for any analyses, interpretations, or conclusions from this study), a career development award from the American Academy of Allergy, Asthma & Immunology (J.S.O.), NIH 5T32CA009140-33 (E.P.H.), and the Penn Center for Clinical Immunology Jackson-Wade Fellowship (E.P.H.)

 Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.

PII: S0091-6749(08)01545-5

doi: 10.1016/j.jaci.2008.08.018

The Journal of Allergy and Clinical Immunology
Volume 122, Issue 6 , Pages 1169-1177.e16 , December 2008

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