The Journal of Allergy and Clinical Immunology
Volume 122, Issue 4 , Pages 685-688 , October 2008

Etiology of asthma exacerbations

  • Annemarie Sykes, MBBS, MSc

      Affiliations

    • Corresponding Author InformationReprint requests: Annemarie Sykes, MBBS, MSc, Department of Respiratory Medicine, National Heart and Lung Institute, MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, Norfolk Place, London W21PG, United Kingdom.
    • ,
  • Sebastian L. Johnston, MBBS, PhD

Received 24 July 2008 ,Revised 6 August 2008 ,Accepted 7 August 2008.

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    Cause of asthma exacerbations. Viral infection is the predominant cause of asthma exacerbations, and synergy exists between allergen sensitization and viral infection. A link between viral infection a

    Cause of asthma exacerbations. Viral infection is the predominant cause of asthma exacerbations, and synergy exists between allergen sensitization and viral infection. A link between viral infection and atypical bacteria is increasingly recognized.

 Disclosure of potential conflict of interest: A. Sykes has received research support from AstraZeneca. S. L. Johnston has received research support from or consulted for Synairgen, Centocor, AstraZeneca, GlaxoSmithKline, Pfizer, and Sanofi Pasteur.

PII: S0091-6749(08)01513-3

doi: 10.1016/j.jaci.2008.08.017

The Journal of Allergy and Clinical Immunology
Volume 122, Issue 4 , Pages 685-688 , October 2008

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