The Journal of Allergy and Clinical Immunology
Volume 122, Issue 3 , Pages 659-660 , September 2008

Allergen immunotherapy: What can and cannot be mixed?

  • Robert E. Esch, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Robert E. Esch, PhD, Research & Development, Greer Laboratories, 639 Nuway Circle, Lenoir, NC 28645.

Received 24 June 2008 ,Revised 23 July 2008 ,Accepted 24 July 2008.

References 

  1. Joint Task Force on Practice Parameters, representing the American Academy of Allergy, Asthma and Immunology, American College of Allergy, Asthma and Immunology . Allergen immunotherapy: a practice parameter, second update. J Allergy Clin Immunol. 2007;120(suppl):S25–S85
  2. Weber RW. Guidelines for using pollen cross-reactivity in formulating allergen immunotherapy. J Allergy Clin Immunol. 2008;122:219–221
  3. Esch RE. Formulation of therapeutic allergen mixtures: problems associated with the number, proportion, and enzymatic activities of allergens. Arb Paul Ehrlich Institut. 2000;93:57–61
  4. Mari A, Scala E. Allergenic extracts for specific immunotherapy: to mix or not to mix?. Int Arch Allergy Immunol. 2006;141:57–60
  5. Grier TJ, LeFevre DM, Duncan EA, Esch RE. Stability of standardized grass, dust mite, cat, and short ragweed extracts after mixing with mold or cockroach extracts. Ann Allergy Asthma Immunol. 2007;99:151–160
  6. American Academy of Allergy, Asthma and Immunology . Support for practicing allergists: extract stability study yields key data. Academy News. 2006;12:9

 Disclosure of potential conflict of interest: R. E. Esch is employed by Greer Laboratories.

PII: S0091-6749(08)01365-1

doi: 10.1016/j.jaci.2008.07.018

The Journal of Allergy and Clinical Immunology
Volume 122, Issue 3 , Pages 659-660 , September 2008

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