The Journal of Allergy and Clinical Immunology
Volume 122, Issue 2 , Pages 254-260.e7 , August 2008

Asthma and the elite athlete: Summary of the International Olympic Committee's Consensus Conference, Lausanne, Switzerland, January 22-24, 2008

  • Kenneth D. Fitch, MBBS, MD

      Affiliations

    • School of Sports Science, Exercise and Health, Faculty of Life Sciences, University of Western Australia, Crawley, Australia
    • Corresponding Author InformationReprint requests: Kenneth D. Fitch, MBBS, MD, School of Sports Science, Exercise and Health, Faculty of Life Sciences, University of Western Australia, M408 Crawley, Western Australia.
  • ,
  • Malcolm Sue-Chu, MBChB, PhD

      Affiliations

    • Department of Lung Medicine, St Olavs Hospital, University Hospital of Trondheim, Trondheim, Norway
    • Department of Circulation and Imaging, Norwegian University of Science and Technology, Trondheim, Norway
  • ,
  • Sandra D. Anderson, PhD, DSc

      Affiliations

    • Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown, Australia
  • ,
  • Louis-Philippe Boulet, MD, FCCP, FRCPC

      Affiliations

    • Institut de Cardiologie et de Pneumologie de l'Université Laval, Hôpital Laval, Laval, Québec, Canada
  • ,
  • Robert J. Hancox, MBChB, MD

      Affiliations

    • Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    • Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
  • ,
  • Donald C. McKenzie, MD, PhD

      Affiliations

    • Division of Sports Medicine and the School of Human Kinetics, University of British Columbia, Vancouver, British Columbia, Canada
  • ,
  • Vibeke Backer, MD, DMSci

      Affiliations

    • Department of Respiratory Medicine L, Bispebjerg University Hospital, Copenhagen, Denmark
  • ,
  • Kenneth W. Rundell, PhD

      Affiliations

    • Human Physiology Laboratory, Marywood University, Scranton, Pa
  • ,
  • Juan M. Alonso, MD

      Affiliations

    • Medical Department, Royal Spanish Athletics Federation, Madrid, Spain
    • Medical and Anti-Doping Commission, International Association of Athletics Federations, Monaco
  • ,
  • Pascale Kippelen, PhD

      Affiliations

    • School of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom
  • ,
  • Joseph M. Cummiskey, MD

      Affiliations

    • Respiratory Medicine, Blackrock Clinic, Dublin, Ireland
  • ,
  • Alain Garnier, MD

      Affiliations

    • World Anti-Doping Agency, Lausanne, Switzerland
  • ,
  • Arne Ljungqvist, MD, PhD

      Affiliations

    • Medical Commission, International Olympic Committee, Lausanne, Switzerland

Received 7 March 2008 ,Revised 3 July 2008 ,Accepted 3 July 2008.

  • Image Result

    Asthma management for the athlete. BD, Bronchodilator; FVC, forced vital capacity.

    Asthma management for the athlete. BD, Bronchodilator; FVC, forced vital capacity.

  • Image Result

    FEV1 changes before and after exercise challenge and after salbutamol following 1 week of salbutamol or placebo treatment. Error bars represent 95% CIs. The mean FEV1 is lower after exercise and durin

    FEV1 changes before and after exercise challenge and after salbutamol following 1 week of salbutamol or placebo treatment. Error bars represent 95% CIs. The mean FEV1 is lower after exercise and during the salbutamol response curve in the salbutamol arm (P < .001). Adapted with permission from Hancox RJ, Subbarao P, Kamada D, Watson RM, Hargreave FE, Inman MD. Beta2-agonist tolerance and exercise-induced bronchospasm. Am J Respir Crit Care Med 2002;165:1068-70.E39

  • Image Result
    Endurance versus nonendurance Olympic Summer Sports 1996 to 2004 mean percentage β2-agonists notified/approved. #Triathlon, estimate because did not participate in 1996; 29 sports because swimming and

    Endurance versus nonendurance Olympic Summer Sports 1996 to 2004 mean percentage β2-agonists notified/approved. #Triathlon, estimate because did not participate in 1996; 29 sports because swimming and synchronized swimming classed separately from diving and water polo.

  • Image Result
    Percentage of athletes notifying (Sydney) or approved (Salt Lake City, Athens, Torino) for β2-agonist use and the percentage of individual medals won by these athletes at the 2000 to 2006 Olympic Game

    Percentage of athletes notifying (Sydney) or approved (Salt Lake City, Athens, Torino) for β2-agonist use and the percentage of individual medals won by these athletes at the 2000 to 2006 Olympic Games.

 Consensus Conference supported by the International Olympic Committee.

 Disclosure of potential conflict of interest: K. D. Fitch is a member of the International Olympic Committee (IOC) Medical Commission and chair of the IOC Independent Asthma Panel. M. Sue-Chu is on the Advisory Board of Novartis and GlaxoSmithKline, has delivered lectures funded by AstraZeneca, has participated in a clinical trial funded by Novartis, and is a member of the IOC Independent Asthma Panel. S. D. Anderson invented the mannitol test for Pharmaxis Ltd and is a member of the IOC Independent Asthma Panel. L.-P. Boulet has received sponsorship or funding from AstraZeneca, GlaxoSmithKline, Merck Frosst, Schering-Plough, Novartis, Alexion, AsthmaTx, Boehringer-Ingelheim, Ception, Genentech, IVAX, MedImmune, Topigen, and Wyeth. D. C. McKenzie has received research funding from the World Anti-Doping Agency and is a member of the IOC Independent Asthma Panel. V. Backer has received research funding from Pharmaxis Ltd and the Danish Lung Association and is a member of the Advisory Board of MSD, Novartis, ALK-Abelló, AstraZeneca, and GlaxoSmithKline. K. W. Rundell has delivered lectures sponsored by Merck and has received research funding from the World Anti-Doping Agency, Pharmaxis, SkyPharma, and Forest Research. P. Kippelen has received research funding from the British Olympic Association and is a member of the IOC Independent Asthma Panel. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(08)01305-5

doi: 10.1016/j.jaci.2008.07.003

The Journal of Allergy and Clinical Immunology
Volume 122, Issue 2 , Pages 254-260.e7 , August 2008