New perspectives on mechanisms underlying chronic allergic inflammation and asthma in 2007
Received 16 June 2008; accepted 19 June 2008. published online 11 August 2008.
This review summarizes selected articles appearing from January to December 2007 in the Journal of Allergy and Clinical Immunology. Articles were chosen that related to advances in mechanisms of chronic allergic inflammation and asthma, including those describing gene association studies, mast cells, IgE, eosinophils, cytokines, the inception of allergy, airway remodeling, preclinical therapeutic targets, and virally induced asthma.
Department of Medicine, University of California San Diego, La Jolla, Calif
Reprint requests: David Broide, MB, ChB, Department of Medicine, University of California San Diego, Biomedical Sciences Building, Room 5090, 9500 Gilman Dr, La Jolla, CA 92093-0635.
Disclosure of potential conflict of interest: D. Broide has consulting arrangements with Indoor Biotech, Allergen, and Amylin and has received research support from the National Institutes of Health, Immune Tolerance Network, and the Food Allergy and Anaphylaxis Network.
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