The Journal of Allergy and Clinical Immunology
Volume 122, Issue 2 , Pages 286-289 , August 2008

Good prognosis, clinical features, and circumstances of peanut and tree nut reactions in children treated by a specialist allergy center

  • Andrew T. Clark, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Andrew T. Clark, MD, Cambridge University Department of Medicine, Box 157 Addenbrooke's Hospital, Cambridge CB2 2QQ, United Kingdom.
    • ,
  • Pamela W. Ewan, FRCP

Received 26 February 2008 ,Revised 12 May 2008 ,Accepted 12 May 2008.

References 

  1. Hourihane JO, Aiken R, Briggs R, Gudgeon LA, Grimshaw KE, DunnGalvin A, et al. The impact of government advice to pregnant mothers regarding peanut avoidance on the prevalence of peanut allergy in United Kingdom children at school entry. J Allergy Clin Immunol. 2007;119:1197–1202
  2. Grundy J, Matthews S, Bateman B, Dean T, Arshad SH. Rising prevalence of allergy to peanut in children: data from 2 sequential cohorts. J Allergy Clin Immunol. 2002;110:784–789
  3. Primeau MN, Kagan R, Joseph L, Lim H, Dufresne C, Duffy C, et al. The psychological burden of peanut allergy as perceived by adults with peanut allergy and the parents of peanut-allergic children. Clin Exp Allergy. 2000;30:1135–1143
  4. Avery NJ, King RM, Knight S, Hourihane JO'B. Assessment of quality of life in children with peanut allergy. Pediatr Allergy Immunol. 2003;14:378–382
  5. Ho MH, Wong WH, Heine RG, Hosking CS, Hill DJ, Allen KJ. Early clinical predictors of remission of peanut allergy in children. J Allergy Clin Immunol. 2008;121:731–736
  6. Hourihane JO, Kilburn SA, Dean P, Warner JO. Clinical characteristics of peanut allergy. Clin Exp Allergy. 1997;27:634–639
  7. Yu JW, Kagan R, Verreault N, Nicolas N, Joseph L, St Pierre Y, et al. Accidental ingestions in children with peanut allergy. J Allergy Clin Immunol. 2006;118:466–472
  8. Bock SA, Atkins FM. The natural history of peanut allergy. J Allergy Clin Immunol. 1989;83:900–904
  9. Vickers DW, Maynard L, Ewan PW. Management of children with potential anaphylactic reactions in the community: a training package and proposal for good practice. Clin Exp Allergy. 1997;27:898–903
  10. Ewan PW, Clark AT. Efficacy of a management plan based on severity assessment in longitudinal and case-controlled studies of 747 children with nut allergy: proposal for good practice. Clin Exp Allergy. 2005;35:751–756
  11. Kapoor S, Roberts G, Bynoe Y, Gaughan M, Habibi P, Lack G. Influence of a multidisciplinary paediatric allergy clinic on parental knowledge and rate of subsequent allergic reactions. Allergy. 2004;59:185–191
  12. Ewan PW, Clark AT. Long-term prospective observational study of patients with peanut and nut allergy after participation in a management plan. Lancet. 2001;357:111–115
  13. Clark AT, Anagnostou K, Ewan PW. Cashew nut causes more severe reactions than peanut: case-matched comparison in 141 children. Allergy. 2007;62:913–916
  14. Vander Leek TK, Liu AH, Stefanski K, Blacker B, Bock SA. The natural history of peanut allergy in young children and its association with serum peanut-specific IgE. J Pediatr. 2000;137:749–755
  15. Sicherer SH, Burks AW, Sampson HA. Clinical features of acute allergic reactions to peanut and tree nuts in children. Pediatrics. 1998;102:e6
  16. Green TD, LaBelle VS, Steele PH, Kim EH, Lee LA, Mankad VS, et al. Clinical characteristics of peanut-allergic children: recent changes. Pediatrics. 2007;120:1304–1310
  17. Tan BM, Sher MR, Good RA, Bahna SL. Severe food allergies by skin contact. Ann Allergy Asthma Immunol. 2001;86:583–586
  18. Simonte SJ, Ma S, Mofidi S, Sicherer SH. Relevance of casual contact with peanut butter in children with peanut allergy. J Allergy Clin Immunol. 2003;112:180–182
  19. Wainstein BK, Kashef S, Ziegler M, Jelley D, Ziegler JB. Frequency and significance of immediate contact reactions to peanut in peanut-sensitive children. Clin Exp Allergy. 2007;37:839–845
  20. Ferdman RM, Church JA. Mixed-up nuts: identification of peanuts and tree nuts by children. Ann Allergy Asthma Immunol. 2006;97:73–77
  21. Clark AT, Ewan PW. The development and progression of allergy to multiple nuts at different ages. Pediatr Allergy Immunol. 2005;16:507–511
  22. Nowak-Wegrzyn A, Conover-Walker MK, Wood RA. Food-allergic reactions in schools and preschools. Arch Pediatr Adolesc Med. 2001;155:790–795
  23. Sicherer SH, Furlong TJ, DeSimone J, Sampson HA. The US Peanut and Tree Nut Allergy Registry: characteristics of reactions in schools and day care. J Pediatr. 2001;138:560–565
  24. Ewan PW. Clinical study of peanut and nut allergy in 62 consecutive patients: new features and associations. BMJ. 1996;312:1074–1078
  25. Sicherer SH, Sampson HA. Peanut allergy: emerging concepts and approaches for an apparent epidemic. J Allergy Clin Immunol. 2007;120:491–503

 Disclosure of potential conflict of interest: A. T. Clark and P. W. Ewan both have received research support from the Food Standards Agency, United Kingdom government.

PII: S0091-6749(08)00951-2

doi: 10.1016/j.jaci.2008.05.015

The Journal of Allergy and Clinical Immunology
Volume 122, Issue 2 , Pages 286-289 , August 2008

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