The Journal of Allergy and Clinical Immunology
Volume 121, Issue 6 , Pages 1455-1459 , June 2008

Soy consumption is not a risk factor for peanut sensitization

  • Jennifer Koplin, BSc (Hons)

      Affiliations

    • Murdoch Children's Research Institute, Melbourne, Australia
    • Department of Pediatrics, University of Melbourne, Melbourne, Australia
    • ,
  • Shyamali C. Dharmage, MBBS, MD, PhD

      Affiliations

    • Center for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne, Australia
    • Corresponding Author InformationReprint requests: Shyamali C. Dharmage, MBBS, MD, PhD, Center for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Level 2, 723 Swanston Street, Carlton VIC 3053 Australia.
    • ,
  • Lyle Gurrin, PhD

      Affiliations

    • Center for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne, Australia
    • ,
  • Nicholas Osborne, PhD

      Affiliations

    • Murdoch Children's Research Institute, Melbourne, Australia
    • Department of Pediatrics, University of Melbourne, Melbourne, Australia
    • ,
  • Mimi L.K. Tang, FRACP, FRCPA, PhD

      Affiliations

    • Murdoch Children's Research Institute, Melbourne, Australia
    • Department of Pediatrics, University of Melbourne, Melbourne, Australia
    • Department of Allergy and Immunology, Royal Children's Hospital, Melbourne, Australia
    • ,
  • Adrian J. Lowe, BBSc (Hons), MPH

      Affiliations

    • Center for Molecular, Environmental, Genetic, and Analytic Epidemiology, University of Melbourne, Melbourne, Australia
    • ,
  • Cliff Hosking, MD, FRACP

      Affiliations

    • John Hunter Children's Hospital, Newcastle, Australia
    • ,
  • David Hill, FRACP

      Affiliations

    • Murdoch Children's Research Institute, Melbourne, Australia
    • ,
  • Katrina J. Allen, FRACP, PhD

      Affiliations

    • Murdoch Children's Research Institute, Melbourne, Australia
    • Department of Pediatrics, University of Melbourne, Melbourne, Australia
    • Department of Allergy and Immunology, Royal Children's Hospital, Melbourne, Australia

Received 19 December 2007 ,Revised 14 February 2008 ,Accepted 20 March 2008.

References 

  1. Grundy J, Matthews S, Bateman B, Dean T, Arshad SH. Rising prevalence of allergy to peanut in children: data from 2 sequential cohorts. J Allergy Clin Immunol. 2002;110:784–789
  2. Sicherer SH, Munoz-Furlong A, Sampson HA. Prevalence of peanut and tree nut allergy in the United States determined by means of a random digit dial telephone survey: a 5-year follow-up study. J Allergy Clin Immunol. 2003;112:1203–1207
  3. Lack G, Fox D, Northstone K, Golding J. Factors associated with the development of peanut allergy in childhood. N Engl J Med. 2003;348:977–985
  4. Sicherer SH, Sampson HA. Peanut allergy: emerging concepts and approaches for an apparent epidemic. J Allergy Clin Immunol. 2007;120:491–503
  5. Khakoo GA, Lack G. Introduction of solids to the infant diet. Arch Dis Child. 2004;89:295
  6. Klemola T, Kalimo K, Poussa T, Juntunen-Backman K, Korpela R, Valovirta E, et al. Feeding a soy formula to children with cow's milk allergy: the development of immunoglobulin E-mediated allergy to soy and peanuts. Pediatr Allergy Immunol. 2005;16:641–646
  7. Hill DJ, Sporik R, Thorburn J, Hosking CS. The association of atopic dermatitis in infancy with immunoglobulin E food sensitization. J Pediatr. 2000;137:475–479
  8. Hill DJ, Hosking CS. Food allergy and atopic dermatitis in infancy: an epidemiologic study. Pediatr Allergy Immunol. 2004;15:421–427
  9. Lowe AJ, Carlin JB, Bennett CM, Abramson MJ, Hosking CS, Hill DJ, et al. Atopic disease and breast-feeding: cause or consequence?. J Allergy Clin Immunol. 2006;117:682–687
  10. Sporik R, Hill DJ, Hosking CS. Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children. Clin Exp Allergy. 2000;30:1540–1546
  11. Venter C, Pereira B, Grundy J, Clayton CB, Roberts G, Higgins B, et al. Incidence of parentally reported and clinically diagnosed food hypersensitivity in the first year of life. J Allergy Clin Immunol. 2006;117:1118–1124
  12. van Wijk F, Knippels L. Initiating mechanisms of food allergy: oral tolerance versus allergic sensitization. Biomed Pharmacother. 2007;61:8–20

 Funding for the initial development of the Melbourne Atopy Cohort Study was provided by Nestlé Australia. J.K. is a recipient of an Australian Postgraduate Award scholarship. K.J.A., S.D., and L.G. are recipients of National Health Medical Research Council Career Development Awards. A.L. is supported by Dairy Australia, Cooperative Research Center for Asthma, and VicHealth. Funding for analysis was also provided by the Ilhan Food Allergy Research Foundation.

 Disclosure of potential conflict of interest: S. Dharmage has received research support from the National Health Medical Research Council, Australia Research Council, and Ilhan Food Allergy Foundation. J. Koplin has received research support from the Ilhan Food Allergy Foundation. L. Gurrin has received research support from National Health Medical Research Council. N. Osborne has received research support from the Ilhan Food Allergy Foundation. M. L. K. Tang was on the advisory board for Nestlé Nutrition Institute, made a presentation at a seminar for Wyeth, and has received research support from Numico, Diroform, and Commonwealth Serum Laboratories. C. Hosking is employed by Melbourne University. D. Hill is on the speakers' bureau for Nutricia International. K. J. Allen has received research support from Ilhan Food Allergy Foundation and the National Health Medical Research Council. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(08)00601-5

doi: 10.1016/j.jaci.2008.03.017

The Journal of Allergy and Clinical Immunology
Volume 121, Issue 6 , Pages 1455-1459 , June 2008

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