The Journal of Allergy and Clinical Immunology
Volume 121, Issue 3 , Pages 725-730.e2 , March 2008

Intrinsically defective skin barrier function in children with atopic dermatitis correlates with disease severity

  • Jayanta Gupta, MD

      Affiliations

    • Division of Epidemiology and Biostatistics, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Institute of Personalized and Predictive Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Emilie Grube, BA

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Mark B. Ericksen, BS

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Institute of Personalized and Predictive Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Michelle D. Stevenson, MD, MS

      Affiliations

    • Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Anne W. Lucky, MD

      Affiliations

    • Division of Pediatric Dermatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Anita P. Sheth, MD

      Affiliations

    • Division of Pediatric Dermatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Amal H. Assa'ad, MD

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Gurjit K. Khurana Hershey, MD, PhD

      Affiliations

    • Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Institute of Personalized and Predictive Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • Corresponding Author InformationReprint requests: Gurjit K. Khurana Hershey, MD, PhD, Institute of Personalized and Predictive Medicine and Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 7028, Cincinnati, OH 45229.

Received 1 October 2007 ,Revised 14 December 2007 ,Accepted 17 December 2007.

References 

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 Supported by National Institutes of Health grant U19A170235-01 (GKKH) and the University of Cincinnati, Molecular Epidemiology in Children's Environmental Health–Institutional NIEHS T32 ES10957 (MDS) and Cincinnati Children's Hospital Medical Center–Institutional NICHD T32 HD43005 (MDS).

 Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.

PII: S0091-6749(07)03611-1

doi: 10.1016/j.jaci.2007.12.1161

The Journal of Allergy and Clinical Immunology
Volume 121, Issue 3 , Pages 725-730.e2 , March 2008

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