The Journal of Allergy and Clinical Immunology
Volume 121, Issue 2, Supplement 2 , Pages A5-A6, February 2008

Information for category 1 CME credit

Article Outline

 

Credit can now be obtained, free for a limited time, by reading the review articles in this issue. Please note the following instructions.

Method of Physician Participation in Learning Process: The core material for these activities can be read in this issue of the Journal or online at the JACI Web site: www.jacionline.org. The accompanying tests may only be submitted online at www.jacionline.org. Fax or other copies will not be accepted.

Date of Original Release: February 2008. Credit may be obtained for these courses until January 31, 2010.

Copyright Statement: Copyright © 2008-2010. All rights reserved.

Overall Purpose/Goal: To provide excellent reviews on key aspects of allergic disease to those who research, treat, or manage allergic disease.

Target Audience: Physicians and researchers within the field of allergic disease.

Accreditation/Provider Statements and Credit Designation: The American Academy of Allergy, Asthma & Immunology (AAAAI) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The AAAAI designates these educational activities for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

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CME article 

“Lymphocytes” 

(page S364)

List of Design Committee Members: Authors: David F. LaRosa, MD, and Jordan S. Orange, MD, PhD

Activity Objectives 


1.To achieve familiarity with the major subpopulations of lymphocytes and their respective functions.

2.To broadly appreciate the developmental influences that give rise to different types of lymphocytes.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: David F. LaRosa and Jordan S. Orange have no significant relationships to disclose.

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CME article 

“Dendritic cells as regulators of immunity and tolerance” 

(page S370)

List of Design Committee Members: Authors: Natalija Novak, MD, and Thomas Bieber, MD, PhD

Activity Objectives 


1.To understand the differential diagnosis for eosinophilia.

2.To identify the indications for use of anti–IL-5 antibody.

3.To identify the genetic abnormalities and pathogenesis of eosinophilic leukemia.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: Natalija Novak has received grants from the German Research Council, Bencard, and LETI Pharma and is on the Novartis advisory board. Thomas Bieber has consultant arrangements with Novartis, Intendis, and Astellas and has received grants/research support from Stallergenes.

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CME article 

“Adhesion molecules and receptors” 

(page S375)

List of Design Committee Members: Author: C. Wayne Smith, MD

Activity Objectives 


1.To learn about the major adhesion molecules involved in leukocyte activation and mobility.

2.To gain an understanding of the major steps in the sequence of adhesive interactions that lead to leukocyte emigration at sites of inflammation.

3.To learn about the major focus in evaluating or targeting adhesion molecules in human diseases.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: C. Wayne Smith has no significant relationships to disclose.

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CME article 

“Gastrointestinal Mucosal immunity” 

(page S380)

List of Design Committee Members: Authors: Barry K. Wershil, MD, and Glenn T. Furuta, MD

Activity Objectives 


1.To recognize the anatomy of the gastrointestinal immune mucosa.

2.To be able to track an antigen from the luminal surface to the mesenteric lymph node.

3.To understand the general differences between lympocyte population in the lamina propria.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: Barry K. Wershil has consulting arrangements with Ception Pharmaceuticals, AstraZeneca, and the National Institutes of Health and is on the speakers' bureau for Shire. Glenn T. Furuta has consulting arrangements with Ception Therapeutics and is on the speakers' bureau for TAP Pharmaceutical.

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CME article 

“Genetics of allergic disease” 

(page S384)

List of Design Committee Members: Authors: John W. Steinke, PhD, Stephen S. Rich, PhD, and Larry Borish, MD

Activity Objectives 


1.To obtain a basic understanding of the types of studies used to examine genetic traits in complex disease such as asthma.

2.To introduce areas in which the field of genetics will be moving in the future with regard to studies of asthma and atopy.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: John W. Steinke, Stephen S. Rich, and Larry Borish have no significant relationships to disclose.

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CME article 

“Secondary immunodeficiencies, including HIV infection” 

(page S388)

List of Design Committee Members: Authors: Javier Chinen, MD, PhD, and William T. Shearer, MD, PhD

Activity Objectives 


1.To define the concept of secondary immunodeficiency as a condition in which nonimmunologic factors suppress immune functions.

2.To study the immunopathogenesis of HIV infection as one the most challenging examples of a secondary immunodeficiency.

3.To enumerate the different factors and conditions that produce secondary immunodeficiency and appreciate that the number of patients with secondary immunodeficiencies far exceeds those with primary (genetic) immunodeficiencies.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: Javier Chinen and William T. Shearer have no significant relationships to disclose.

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CME article 

“Immunologic lung disease” 

(page S393)

List of Design Committee Members: Author: Paul A. Greenberger, MD

Activity Objectives 


1.To review the differences between the CD4TH1+ and CD4TH2+ granulomatous pulmonary diseases.

2.To understand the clinical and immunologic findings of hypersensitivity pneumonitis.

3.To consider the differential diagnosis of pulmonary eosinophilic conditions.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: Paul A. Greenberger has consulting arrangements with Novartis and Genetech and has received grant support from the National Heart, Lung, and Blood Institute.

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CME article 

“Hereditary angioedema” 

(page S398)

List of Design Committee Members: Author: Michael M. Frank, MD

Activity Objectives 


1.To understand the clinical presentation of hereditary angioedema.

2.To have a working knowledge of approaches to therapy currently available in the United States.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: Michael M. Frank has consulting arrangements with Lev Pharmaceuticals, CSL Behring, Jerini, and Dyax; has received grant support from Lev Pharmaceuticals and CLS Behring; and has served as an expert witness for Jerini.

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CME article 

“Anaphylaxis” 

(page S402)

List of Design Committee Members: Author: F. Estelle R. Simons, MD, FRCPC

Activity Objectives 


1.To describe the pathogenesis of anaphylaxis.

2.To state the basic principles of diagnosis and risk assessment in anaphylaxis.

3.To discuss management of acute anaphylaxis and long-term risk reduction in anaphylaxis.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: F. Estelle R. Simons has no significant relationships to disclose.

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CME article 

“Occupational asthma” 

(page S408)

List of Design Committee Members: Author: Emil J. Bardana, Jr, MD, CM

Activity Objectives 


1.To understand the definition and classification of new-onset occupational asthma.

2.To summarize the various factors that may influence the development of occupational asthma.

3.To identify valid approaches to the diagnosis of occupational asthma.

Recognition of Commercial Support: This CME activity has not received external commercial support.

Disclosure of Significant Relationships with Relevant Commercial Companies/Organizations: Emil J. Bardana, Jr, has served as an expert witness in civil litigation and worker's compensation independent medical examinations for the states of Alaska, Washington, Idaho, and Montana.

PII: S0091-6749(07)02387-1

doi:10.1016/S0091-6749(07)02387-1

The Journal of Allergy and Clinical Immunology
Volume 121, Issue 2, Supplement 2 , Pages A5-A6, February 2008