The Journal of Allergy and Clinical Immunology
Volume 121, Issue 3 , Pages 731-736 , March 2008

Early clinical predictors of remission of peanut allergy in children

  • Marco H.K. Ho, MD

      Affiliations

    • Department of Allergy and Immunology, Royal Children's Hospital, Melbourne, Australia
    • ,
  • Wilfred H.S. Wong, MMedSc

      Affiliations

    • Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China
    • ,
  • Ralf G. Heine, MD

      Affiliations

    • Department of Allergy and Immunology, Royal Children's Hospital, Melbourne, Australia
    • Murdoch Children's Research Institute, Melbourne, Australia
    • Department of Pediatrics, The University of Melbourne, Melbourne, Australia
    • ,
  • Clifford S. Hosking, MD

      Affiliations

    • John Hunter Children's Hospital, Newcastle, Australia
    • ,
  • David J. Hill, MD

      Affiliations

    • Murdoch Children's Research Institute, Melbourne, Australia
    • ,
  • Katrina J. Allen, MD, PhD

      Affiliations

    • Department of Allergy and Immunology, Royal Children's Hospital, Melbourne, Australia
    • Murdoch Children's Research Institute, Melbourne, Australia
    • Department of Pediatrics, The University of Melbourne, Melbourne, Australia
    • Corresponding Author InformationReprint requests: Katrina J. Allen, MD, PhD, Pediatric Gastroenterologist/Allergist, Department of Allergy and Immunology, Royal Children's Hospital, Flemington Rd, Parkville Vic 3052, Australia.

Received 16 June 2007 ,Revised 10 October 2007 ,Accepted 16 November 2007.

  • Image Result

    Evolution of SPT wheal size to peanut over the first 10 years of age. Shaded boxes represent the nonremitter group; open boxes represent the remitter group. The box represents the interquartile range,

    Evolution of SPT wheal size to peanut over the first 10 years of age. Shaded boxes represent the nonremitter group; open boxes represent the remitter group. The box represents the interquartile range, and the whiskers represent the 95% CIs of the means. SPT wheal diameters of nonremitters constantly increase (∗r = 0.31, P < .001) and those of remitters decrease (#r = −0.26, P = .002) between the age of 1 and 4 years.

 Dr Ho was supported by the Ho Hung Chiu Medical Education Scholarship and training grant of the Hospital Authority, Hong Kong SAR, China. Dr Allen is a recipient of an Australian National Health and Medical Research Council Career Development Award and has funding from the Ilhan Food Allergy Foundation and AnaphylaxiStop.

 Disclosure of potential conflict of interest: The authors have declared that they have no relevant conflict of interest.

PII: S0091-6749(07)02262-2

doi: 10.1016/j.jaci.2007.11.024

The Journal of Allergy and Clinical Immunology
Volume 121, Issue 3 , Pages 731-736 , March 2008

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