The Journal of Allergy and Clinical Immunology
Volume 121, Issue 1 , Pages 38-42.e3 , January 2008

Cigarette smoking and allergic sensitization: A 32-year population-based cohort study

  • Robert J. Hancox, MD

      Affiliations

    • Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    • Corresponding Author InformationReprint requests: Robert J. Hancox, MD, Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand.
    • ,
  • David Welch, PhD

      Affiliations

    • Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    • ,
  • Richie Poulton, PhD

      Affiliations

    • Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    • ,
  • D. Robin Taylor, MD

      Affiliations

    • Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    • ,
  • Christene R. McLachlan, MApplSci

      Affiliations

    • Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    • ,
  • Justina M. Greene, DipCompSys

      Affiliations

    • Firestone Institute for Respiratory Health, Department of Medicine, Hamilton, Ontario, Canada
    • ,
  • Malcolm R. Sears, MB

      Affiliations

    • Firestone Institute for Respiratory Health, Department of Medicine, Hamilton, Ontario, Canada

Received 12 June 2007 ,Revised 25 September 2007 ,Accepted 26 September 2007.

  • Image Result

    Prevalence of allergic sensitization at age 13 years. Percent of 13-year-olds with positive SPT results to any allergen, grass, dust mite, and cat in those with and without a parental history of atopy

    Prevalence of allergic sensitization at age 13 years. Percent of 13-year-olds with positive SPT results to any allergen, grass, dust mite, and cat in those with and without a parental history of atopy. Open bars indicate those with nonsmoking parents; solid bars indicate those with parents who smoked. ∗P < .05.

  • Image Result
    Development of allergic sensitization between ages 13 and 32 years. Percent of 32-year-olds with positive SPT results to any allergen, grass, dust mite, and cat in those with and without parental atop

    Development of allergic sensitization between ages 13 and 32 years. Percent of 32-year-olds with positive SPT results to any allergen, grass, dust mite, and cat in those with and without parental atopy. Individuals with any positive SPT results at age 13 years are excluded. Open bars indicate never or exsmokers; solid bars indicate current smokers. ∗P < .05.

 The Dunedin Multidisciplinary Health and Development Research Unit is supported by the Health Research Council of New Zealand. M.R.S. holds the AstraZeneca Chair in Respiratory Epidemiology at McMaster University.

 Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.

PII: S0091-6749(07)01954-9

doi: 10.1016/j.jaci.2007.09.052

The Journal of Allergy and Clinical Immunology
Volume 121, Issue 1 , Pages 38-42.e3 , January 2008

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