The natural history of egg allergy

Egg allergy resolution over time. Graphs represent Kaplan-Meier survival curves for development of tolerance to egg over time using 3 definitions for tolerance.

Trend in egg IgE levels over time by final egg allergy status. Scatter plots of all egg IgE levels recorded by age (n = 2681). A, All values in the group with persistent egg allergy (n = 2192). B, All values in the group that eventually resolved egg allergy (n = 489). Nonparametric smoothed curves show the trend in egg IgE levels over time.

Relationship of peak egg IgE level and resolution of egg allergy. Survival curves for each stratum of peak egg IgE level. Number of patients in each stratum: <2 kU/L (n = 155); 2-4.9 (n = 131); 5-9.9 (n = 125); 10-19.9 (n = 118); 20-49.9 (n = 103); 50+ (n = 162). Number of patients remaining at the final time point analyzed for each stratum: <2 kU/L (n = 3); 2-4.9 (n = 3); 5-9.9 (n = 3); 10-19.9 (n = 2); 20-49.9 (n = 1); 50+ (n = 1).