The Journal of Allergy and Clinical Immunology
Volume 119, Issue 6 , Pages 1470-1480 , June 2007

Chemokine responses distinguish chemical-induced allergic from irritant skin inflammation: Memory T cells make the difference

  • Stephan Meller, MD

      Affiliations

    • From the Department of Dermatology, Heinrich-Heine-University, Düsseldorf
    • These authors contributed equally to this work.
  • ,
  • Antti I. Lauerma, MD, PhD

      Affiliations

    • Control of Hypersensitivity Diseases, Finnish Institute of Occupational Health, Helsinki
    • These authors contributed equally to this work.
  • ,
  • Frank Michael Kopp, PhD

      Affiliations

    • Institute of Environmental Research, Heinrich-Heine University, Düsseldorf
    • These authors contributed equally to this work.
  • ,
  • Franziska Winterberg, PhD

      Affiliations

    • From the Department of Dermatology, Heinrich-Heine-University, Düsseldorf
    • These authors contributed equally to this work.
  • ,
  • Minna Anthoni, PhD

      Affiliations

    • Control of Hypersensitivity Diseases, Finnish Institute of Occupational Health, Helsinki
  • ,
  • Anja Müller, MD

      Affiliations

    • Department of Radiation Oncology, Heinrich-Heine University, Düsseldorf
  • ,
  • Michael Gombert, PhD

      Affiliations

    • From the Department of Dermatology, Heinrich-Heine-University, Düsseldorf
  • ,
  • Anna Haahtela, PhD

      Affiliations

    • Skin and Allergy Hospital, Helsinki University Central Hospital
  • ,
  • Harri Alenius, PhD

      Affiliations

    • Centre of Excellence in Immunotoxicology, Finnish Institute of Occupational Health, Helsinki
  • ,
  • Juliane Rieker, MD

      Affiliations

    • From the Department of Dermatology, Heinrich-Heine-University, Düsseldorf
  • ,
  • Marie-Caroline Dieu-Nosjean, PhD

      Affiliations

    • Institut National de la Santé et de la Recherche Médicale Unité 255, Laboratoire d'Immunologie Cellulaire et Clinique, Centre de Recherches Biomédicales des Cordeliers, Paris
  • ,
  • Robert Christof Kubitza

      Affiliations

    • From the Department of Dermatology, Heinrich-Heine-University, Düsseldorf
  • ,
  • Ernst Gleichmann, MD

      Affiliations

    • Institute of Environmental Research, Heinrich-Heine University, Düsseldorf
  • ,
  • Thomas Ruzicka, MD

      Affiliations

    • From the Department of Dermatology, Heinrich-Heine-University, Düsseldorf
  • ,
  • Albert Zlotnik, PhD

      Affiliations

    • Neurocrine Bioscience, San Diego
  • ,
  • Bernhard Homey, MD

      Affiliations

    • From the Department of Dermatology, Heinrich-Heine-University, Düsseldorf
    • Corresponding Author InformationReprint requests: Bernhard Homey, MD, Department of Dermatology, Heinrich-Heine-University, Moorenstr. 5, D-40225 Düsseldorf, Germany.

Received 9 August 2006 ,Revised 22 November 2006 ,Accepted 12 December 2006.

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 Supported by Contract QLK4-CT-2001-00366 Chemokine-Atopy from the European Commission (to A.I.L., B.H., H.A.) and by Grant SFB503/C9 from the German Research Foundation (to B.H.).Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest.

PII: S0091-6749(07)00115-7

doi: 10.1016/j.jaci.2006.12.654

The Journal of Allergy and Clinical Immunology
Volume 119, Issue 6 , Pages 1470-1480 , June 2007