The Journal of Allergy and Clinical Immunology
Volume 119, Issue 4 , Pages 930-936 , April 2007

Staphylococcus aureus sensitization and allergic disease in early childhood: Population-based birth cohort study

  • Aida Semic-Jusufagic, MD

      Affiliations

    • From the University of Manchester
    • Corresponding Author InformationReprint requests: Aida Semic-Jusufagic, MD, University of Manchester, North West Lung Centre, Wythenshawe Hospital, Manchester M23 9LT, United Kingdom.
    • ,
  • Claus Bachert, MD, PhD

      Affiliations

    • University of Ghent
    • ,
  • Philippe Gevaert, MD

      Affiliations

    • University of Ghent
    • ,
  • Gabriele Holtappels, BSc

      Affiliations

    • University of Ghent
    • ,
  • Lesley Lowe, PhD

      Affiliations

    • From the University of Manchester
    • ,
  • Ashley Woodcock, MD, FRCP

      Affiliations

    • From the University of Manchester
    • ,
  • Angela Simpson, MD, MRCP

      Affiliations

    • From the University of Manchester
    • ,
  • Adnan Custovic, MD, PhD

      Affiliations

    • From the University of Manchester

Received 26 September 2006 ,Revised 12 December 2006 ,Accepted 14 December 2006.

  • Image Result

    Study profile.

    Study profile.

  • Image Result

    A, SE-mix sensitization and eczema severity in the whole population. B, SE-mix sensitization and the frequency of wheezy episodes within the previous 12 months in the whole population.

    A, SE-mix sensitization and eczema severity in the whole population. B, SE-mix sensitization and the frequency of wheezy episodes within the previous 12 months in the whole population.

  • Image Result

    SE-mix sensitization, current wheeze, and eczema among atopic children.

    SE-mix sensitization, current wheeze, and eczema among atopic children.

  • Image Result

    Bronchial hyperreactivity defined as postchallenge FEV1 change in percentage among SE-mix–sensitized and nonsensitized wheezers (means and 95% CIs).

    Bronchial hyperreactivity defined as postchallenge FEV1 change in percentage among SE-mix–sensitized and nonsensitized wheezers (means and 95% CIs).

 Supported by Asthma UK grant #04/014 and a grant from the Flemish Scientific Research Board, Fonds voor Wetenschappelijk Onderzoek, Nr A12/5-K/V-K17.Disclosure of potential conflict of interest: All of the authors have received grant support from Asthma UK and the Flemish Scientific Research Board.

PII: S0091-6749(06)03908-X

doi: 10.1016/j.jaci.2006.12.639

The Journal of Allergy and Clinical Immunology
Volume 119, Issue 4 , Pages 930-936 , April 2007

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