« Previous Next » The Journal of Allergy and Clinical Immunology
Volume 119, Issue 1 , Pages 64-72 , January 2007

Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: The Pediatric Asthma Controller Trial

Christine A. Sorkness, PharmD
- Clinical Science Center, University of Wisconsin, Madison
- Reprint requests: Christine A. Sorkness, PharmD, K4/950 University of Wisconsin Clinical Science Center, 600 Highland Avenue, Madison, WI 53792-3244.
Robert F. Lemanske Jr., MD
- Clinical Science Center, University of Wisconsin, Madison
David T. Mauger, PhD
- Department of Health Evaluation Sciences, Pennsylvania State University, Hershey
Susan J. Boehmer, MA
- Department of Health Evaluation Sciences, Pennsylvania State University, Hershey
Vernon M. Chinchilli, PhD
- Department of Health Evaluation Sciences, Pennsylvania State University, Hershey
Fernando D. Martinez, MD
- From the Arizona Respiratory Center, University of Arizona, Tucson
Robert C. Strunk, MD
- Department of Pediatrics, Washington University, St Louis
Stanley J. Szefler, MD
- Department of Pediatrics, National Jewish and Research Center and University of Colorado Health Sciences Center, Denver
Robert S. Zeiger, MD, PhD
- Department of Pediatrics, University of California–San Diego
- Department of Allergy, Kaiser Permanente, San Diego
Leonard B. Bacharier, MD
- Department of Pediatrics, Washington University, St Louis
Gordon R. Bloomberg, MD
- Department of Pediatrics, Washington University, St Louis
Ronina A. Covar, MD
- Department of Pediatrics, National Jewish and Research Center and University of Colorado Health Sciences Center, Denver
Theresa W. Guilbert, MD
- From the Arizona Respiratory Center, University of Arizona, Tucson
Gregory Heldt, MD
- Department of Pediatrics, University of California–San Diego
Gary Larsen, MD
- Department of Pediatrics, National Jewish and Research Center and University of Colorado Health Sciences Center, Denver
Michael H. Mellon, MD
- Department of Allergy, Kaiser Permanente, San Diego
Wayne J. Morgan, MD
- From the Arizona Respiratory Center, University of Arizona, Tucson
Mark H. Moss, MD
- Clinical Science Center, University of Wisconsin, Madison
Joseph D. Spahn, MD
- Department of Pediatrics, National Jewish and Research Center and University of Colorado Health Sciences Center, Denver
Lynn M. Taussig, MD
- Department of Pediatrics, National Jewish and Research Center and University of Colorado Health Sciences Center, Denver
for the Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute

Received 9 June 2006 ,Revised 30 August 2006 ,Accepted 5 September 2006.

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Supported by grants HL064307, HL64288, HL064295, HL64287, and HL064305 from the National Heart, Lung and Blood Institute. This study was performed in part by the General Clinical Research Centers at Washington University School of Medicine (M01 RR00036), National Jewish Medical and Research Center (M01 RR00051), and the University of Wisconsin (M01 RR03186).Disclosure of potential conflict of interest: C. A. Sorkness has consultant arrangements with GlaxoSmithKline and AstraZeneca, has received grant support from GlaxoSmithKline and Pharmaxis, and is on the speakers' bureau for GlaxoSmithKline and Genentech. R. F. Lemanske has consultant arrangements with GlaxoSmithKline, Merck, AstraZeneca, Aventis, and Novartis, has received grant support from the National Heart, Lung, and Blood Institute (NHLBI), and is on the speakers' bureau for Merck, AstraZeneca, GlaxoSmithKline, and Aventis. D. T. Mauger, S. J. Boehmer, and V. M. Chinchilli have received grant support from the National Institutes of Health (NIH). F. D. Martinez has had consultant arrangements with Genentech and Pfizer, has served on the advisory board for Merck, and has received an honorarium for a lecture at a meeting sponsored by Merck. S. J. Szefler has consultant arrangements with AstraZeneca, GlaxoSmithKline, Aventis, Genentech, and Merck, and has received grant support from the NIH, NHLBI, National Institute of Allergy and Infectious Diseases, and Ross Pharmaceuticals. R. S. Zeiger has consultant arrangements with Aerocrine, AstraZeneca, Genentech, GlaxoSmithKline, Merck, Novartis, and Sanofi-Aventis, and has received grant support from AstraZeneca, GlaxoSmithKline, Merck, Sanofi-Aventis, and TEVA Pharmaceuticals. L. B. Bacharier has received grant support from the NIH and NHLBI, and is on the speakers' bureau for Merck, GlaxoSmithKline, AstraZeneca, and Genentech. R. A. Covar has received grant support from AstraZeneca. T. W. Guilbert has participated on an advisory board sponsored by GlaxoSmithKline and as a consultant in the design of Continuing Medical Education (CME) courses and for asthma for the Innovia Medical Educational Institute, and has received consultant fees from GlaxoSmithKline and stocks or revenue from speakers' bureaus, research, or grant activities from GlaxoSmithKline, AstraZeneca, Merck, and Pfizer, and is on the speakers' bureau for GlaxoSmithKline, AstraZeneca, SOMA Medical Education (CME), Innovia Medical Education Institute (CME), Antidote (formerly Medical World Conferences, CME), and Health Matters. G. Larsen has consultant arrangements with GlaxoSmithKline and Schering Plough, and has received grant support from the NIH. M. H. Mellon is on the speakers' bureau for AstraZeneca, Schering Plough, and Altana. W. J. Morgan has consultant arrangements with Genentech and has patent licensing arrangements with the Wisconsin Alumni Research Foundation. J. D. Spahn has consultant arrangements with GlaxoSmithKline and AstraZeneca, has received grant support from Merck, AstraZeneca, and GlaxoSmithKline, and is on the speakers' bureau for GlaxoSmithKline. L. M. Taussig has consultant arrangements with GlaxoSmithKline. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(06)02122-1

doi: 10.1016/j.jaci.2006.09.042

« Previous Next » The Journal of Allergy and Clinical Immunology
Volume 119, Issue 1 , Pages 64-72 , January 2007