The Journal of Allergy and Clinical Immunology
Volume 119, Issue 1 , Pages 192-198 , January 2007

Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: A randomized, double-blind, placebo-controlled trial

  • Kaarina Kukkonen, MD

      Affiliations

    • From the Skin and Allergy Hospital, University of Helsinki
    • Corresponding Author InformationReprint requests: Kaarina Kukkonen, MD, Helsinki University Central Hospital, the Skin and Allergy Hospital, Meilahdentie 2, PO Box 160, 00029 HUCH Helsinki, Finland.
  • ,
  • Erkki Savilahti, MD, PhD

      Affiliations

    • Hospital for Children and Adolescents, University of Helsinki
  • ,
  • Tari Haahtela, MD, PhD

      Affiliations

    • From the Skin and Allergy Hospital, University of Helsinki
  • ,
  • Kaisu Juntunen-Backman, MD, PhD

      Affiliations

    • From the Skin and Allergy Hospital, University of Helsinki
  • ,
  • Riitta Korpela, PhD

      Affiliations

    • Institute of Biomedicine, Pharmacology, University of Helsinki
    • Valio Research and Development, Helsinki
  • ,
  • Tuija Poussa, MSc

      Affiliations

    • STAT-consulting, Tampere
  • ,
  • Tuula Tuure, PhD

      Affiliations

    • Valio Research and Development, Helsinki
  • ,
  • Mikael Kuitunen, MD, PhD

      Affiliations

    • From the Skin and Allergy Hospital, University of Helsinki

Received 9 June 2006 ,Revised 7 September 2006 ,Accepted 11 September 2006.

  • Image Result

    Diagram showing the flow of participants in the probiotic and placebo groups.

    Diagram showing the flow of participants in the probiotic and placebo groups.

 Supported by the Helsinki University Central Hospital Research Funds and Valio Ltd, Helsinki, Finland. Part-time monthly salaries that M.K. received and monthly salaries that K.K. received from the Clinical Research Institute Helsinki University Central Hospital Ltd were funded by Valio Ltd.Disclosure of potential conflict of interest: K. Kukkonen has received grant support from Valio Ltd. R. Korpela and T. Tuure are employed by Valio Ltd and by R&D. T. Poussa has consultant arrangements with Valio Ltd. M. Kuitunen has received grant support from Valio Ltd. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(06)01908-7

doi: 10.1016/j.jaci.2006.09.009

The Journal of Allergy and Clinical Immunology
Volume 119, Issue 1 , Pages 192-198 , January 2007