The Journal of Allergy and Clinical Immunology
Volume 118, Issue 3 , Pages 682-690 , September 2006

Distribution and determinants of house dust mite allergens in Europe: The European Community Respiratory Health Survey II

  • Jan-Paul Zock, PhD

      Affiliations

    • From the Center for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona
    • Corresponding Author InformationReprint requests: Jan-Paul Zock, PhD, IMIM, Dr Aiguader 80, E-08003 Barcelona, Spain.
  • ,
  • Joachim Heinrich, PhD

      Affiliations

    • National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg
  • ,
  • Deborah Jarvis, MD

      Affiliations

    • Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College, London
  • ,
  • Giuseppe Verlato, MD, PhD

      Affiliations

    • Department of Medicine and Public Health, University of Verona
  • ,
  • Dan Norbäck, PhD

      Affiliations

    • Department of Medical Science, Occupational and Environmental Medicine, Uppsala University
  • ,
  • Estel Plana, MSc

      Affiliations

    • From the Center for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona
  • ,
  • Jordi Sunyer, MD, PhD

      Affiliations

    • From the Center for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona
  • ,
  • Susan Chinn, DSc

      Affiliations

    • Department of Public Health Sciences, King's College London
  • ,
  • Mario Olivieri, MD

      Affiliations

    • Unit of Occupational Medicine, University of Verona
  • ,
  • Argo Soon, PhD

      Affiliations

    • Department of Public Health, University of Tartu
  • ,
  • Simona Villani, PhD

      Affiliations

    • Department of Health Sciences, Section of Epidemiology and Medical Statistics, University of Pavia
  • ,
  • Michela Ponzio, PhD

      Affiliations

    • Department of Health Sciences, Section of Epidemiology and Medical Statistics, University of Pavia
  • ,
  • Anna Dahlman-Hoglund, PhD

      Affiliations

    • Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Göteborg
  • ,
  • Cecilie Svanes, MD, PhD

      Affiliations

    • Department of Thoracic Medicine, Institute of Medicine, University of Bergen
  • ,
  • Christina Luczynska, PhD

      Affiliations

    • Department of Public Health Sciences, King's College London
    • Deceased.
  • ,
  • for the Indoor Working Group of the European Community Respiratory Health Survey II

Received 22 December 2005 ,Revised 7 April 2006 ,Accepted 10 April 2006.

  • Image Result

    Distribution of Der p 1 and Der f 1 allergens in Europe (based on 3414 measurements in 22 study centers from 10 countries). Percentages of dust samples with detectable mite allergen levels (ie, ≥0.1 μ

    Distribution of Der p 1 and Der f 1 allergens in Europe (based on 3414 measurements in 22 study centers from 10 countries). Percentages of dust samples with detectable mite allergen levels (ie, ≥0.1 μg per gram of dust) are shown. Results for adjacent centers within the same country with similar results were combined (Ipswich and Norwich in East Anglia, United Kingdom; Pavia, Turin, and Verona in Northern Italy; Antwerp Center and Antwerp South in Belgium).

  • Image Result
    Ecological association between winter temperature and geometric mean Der p 1 (A) and Der f 1 (B) concentrations. Metaregression models for log-transformed allergen level on temperature in the coldest

    Ecological association between winter temperature and geometric mean Der p 1 (A) and Der f 1 (B) concentrations. Metaregression models for log-transformed allergen level on temperature in the coldest month by center. The circle sizes indicate the relative contribution of each center to the regression estimate.

 The coordination of ECRHS II was supported by the European Commission as part of their Quality of Life program. The following bodies funded the local studies in ECRHS II included in this article: Albacete: Fondo de Investigaciones Santarias (grant code: 97/0035-01, 99/0034-01, and 99/0034-02), Hospital Universitario de Albacete, Consejería de Sanidad; Antwerp: Fund for Scientific Research-Flanders Belgium (grant code: G.0402.00), University of Antwerp, Flemish Health Ministry; Barcelona: Spanish Respiratory Society (SEPAR), Public Health Service (grant code: R01 HL62633-01), Fondo de Investigaciones Santarias (grant code: 97/0035-01, 99/0034-01, and 99/0034-02), Interdepartmental Council of Technological Research and Innovation (CIRIT) (grant code: 1999SGR 00241), Red Respira Carlos III Health Institute; Basel: Swiss National Science Foundation, Swiss Federal Office for Education and Science, Swiss National Accident Insurance Fund, USC National Institute of Environmental Health Sciences Center grant 5P30 ES07048; Erfurt: GSF–National Research Center for Environment and Health, Deutsche Forschungsgemeinschaft (grant code FR 1526/1-1); Galdakao: Basque Health Department; Göteborg: Swedish Heart Lung Foundation, Swedish Foundation for Health Care Sciences and Allergy Research, Swedish Asthma and Allergy Foundation, Swedish Cancer and Allergy Foundation; Grenoble: Programme Hospitalier de Recherche Clinique-DRC de Grenoble 2000 #2610, Ministry of Health, Direction de la Recherche Clinique, Ministere de l'Emploi et de la Solidarite, Direction Generale de la Sante, CHU de Grenoble, Comite des Maladies Respiratoires de l'Isere; Hamburg: GSF–National Reasearch Center for Environment and Health, Deutsche Forschungsgemeinschaft (grant code MA 711/4-1); Ipswich and Norwich: Asthma UK (formerly known as National Asthma Campaign); Huelva: Fondo de Investigaciones Santarias (grant code: 97/0035-01, 99/0034-01 and 99/0034-02); Oviedo: Fondo de Investigaciones Santarias (grant code: 97/0035-01, 99/0034-01, and 99/0034-02); Paris: Ministère de l'Emploi et de la Solidarité, Direction Generale de la Sante, UCB-Pharma (France), Aventis (France), Glaxo France, Programme Hospitalier de Recherche Clinique–DRC de Grenoble 2000 #2610, Ministry of Health, Direction de la Recherche Clinique, CHU de Grenoble; Pavia: Glaxo-SmithKline Italy, Italian Ministry of University and Scientific and Technological Research, Local University Funding for research 1998 and 1999 (Pavia, Italy); Reykjavik: Icelandic Research Council, Icelandic University Hospital Fund; Tartu: Estonian Science Foundation; Turin: ASL 4 Regione Piemonte (Italy), AO CTO/ICORMA Regione Piemonte (Italy), Italian Ministry of University and Scientific and Technological Research; GlaxoSmithKline Italy; Umeå: Swedish Heart Lung Foundation, Swedish Foundation for Health Care Sciences and Allergy Research, Swedish Asthma and Allergy Foundation, Swedish Cancer and Allergy Foundation; Uppsala: Swedish Heart Lung Foundation, Swedish Foundation for Health Care Sciences and Allergy Research, Swedish Asthma and Allergy Foundation, Swedish Cancer and Allergy Foundation; Verona: University of Verona; Italian Ministry of University and Scientific and Technological Research; GlaxoSmithKline Italy.Disclosure of potential conflict of interest: A. Soon has received grant support from the Estonian Science Foundation. The rest of the authors have declared that they have no conflict of interest.

PII: S0091-6749(06)01363-7

doi: 10.1016/j.jaci.2006.04.060

The Journal of Allergy and Clinical Immunology
Volume 118, Issue 3 , Pages 682-690 , September 2006