The Journal of Allergy and Clinical Immunology
Volume 116, Issue 6 , Pages 1213-1219 , December 2005

Irreversible lung function deficits in young adults with a history of childhood asthma

  • Susan L. Limb, MD

      Affiliations

    • From the Division of Allergy and Clinical Immunology
    • ,
  • Kathryn C. Brown, MD

      Affiliations

    • From the Division of Allergy and Clinical Immunology
    • ,
  • Robert A. Wood, MD

      Affiliations

    • Department of Pediatrics
    • ,
  • Robert A. Wise, MD

      Affiliations

    • Divisions of Pulmonology and Critical Care Medicine, Johns Hopkins School of Medicine
    • ,
  • Peyton A. Eggleston, MD

      Affiliations

    • Department of Pediatrics
    • ,
  • James Tonascia, PhD

      Affiliations

    • Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University
    • ,
  • N. Franklin Adkinson Jr., MD

      Affiliations

    • From the Division of Allergy and Clinical Immunology
    • Corresponding Author InformationReprint requests: N. Franklin Adkinson, Jr, MD, JHAAC Rm 2A.62, 5501 Hopkins Bayview Circle, Baltimore, MD 21224.

Received 8 August 2005 ,Revised 13 September 2005 ,Accepted 19 September 2005.

  • Image Result

    Percentiles based on National Health and Nutrition Examination Survey III normative data and percent predicted values for postbronchodilator spirometric measures at initial adult evaluation (n = 84).

    Percentiles based on National Health and Nutrition Examination Survey III normative data and percent predicted values for postbronchodilator spirometric measures at initial adult evaluation (n = 84). Axes for estimated corresponding percent predicted values are displayed as insets (exact correspondence of measures varies with age, sex, height, and ethnicity). Mean FEV1 percent predicted = 91.2%; mean FVC = 102.8%; mean FEV1/FVC ratio = 88.6%.

  • Image Result
    Correlations between childhood and young adult prebronchodilator spirometric results: normal (open circles) and abnormal (filled circles) categorization on the basis of spirometry in young adulthood.

    Correlations between childhood and young adult prebronchodilator spirometric results: normal (open circles) and abnormal (filled circles) categorization on the basis of spirometry in young adulthood.

 Supported by the Philip Morris External Research Program and National Institutes of Health, National Center for Research Resources, grant no. 5M01RR02719 to The Johns Hopkins Bayview General Clinical Research Center.

PII: S0091-6749(05)02110-X

doi: 10.1016/j.jaci.2005.09.024

The Journal of Allergy and Clinical Immunology
Volume 116, Issue 6 , Pages 1213-1219 , December 2005

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