The Journal of Allergy and Clinical Immunology
Volume 115, Issue 5 , Pages 1089-1090 , May 2005

COX-2–selective inhibitor valdecoxib induces severe allergic skin reactions

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    Severe allergic skin reactions to valdecoxib. A, A 58-year-old patient with a generalized maculopapular exanthem induced by valdecoxib. B, Severe and spreading skin reaction 48 hours after scratch tes

    Severe allergic skin reactions to valdecoxib. A, A 58-year-old patient with a generalized maculopapular exanthem induced by valdecoxib. B, Severe and spreading skin reaction 48 hours after scratch testing with valdecoxib. C, Skin reaction (+++) day 2 after epicutaneous patch testing with valdecoxib (at a concentration of 10% in the upper reaction and 1% in the reaction below).

PII: S0091-6749(05)00116-8

doi: 10.1016/j.jaci.2004.12.1135

The Journal of Allergy and Clinical Immunology
Volume 115, Issue 5 , Pages 1089-1090 , May 2005