The Journal of Allergy and Clinical Immunology
Volume 114, Issue 5 , Pages 1189-1194 , November 2004

Immune responses to mosquito saliva in 14 individuals with acute systemic allergic reactions to mosquito bites

  • Zhikang Peng, MD

      Affiliations

    • From the Section of Allergy and Clinical Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg
    • Corresponding Author InformationReprint requests: Zhikang Peng, MD, Department of Pediatrics and Child Health, University of Manitoba, 532-715 McDermot Ave, Winnipeg, Manitoba, Canada, R3E 3P4.
  • ,
  • Andrew N. Beckett, BSc

      Affiliations

    • From the Section of Allergy and Clinical Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg
  • ,
  • Renata J. Engler, MD

      Affiliations

    • Walter Reed Army Medical Center, Washington
  • ,
  • Donald R. Hoffman, PhD

      Affiliations

    • Department of Pathology and Laboratory Medicine, East Carolina University, Greenville
  • ,
  • Nancy L. Ott, MD

      Affiliations

    • Southdale Pediatric Associates, Ld, Edina
  • ,
  • F. Estelle R. Simons, MD, FRCPC

      Affiliations

    • From the Section of Allergy and Clinical Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg

Received 3 June 2004 ,Revised 5 August 2004 ,Accepted 6 August 2004.

  • Image Result

    Mean mosquito saliva–specific IgE levels in individuals with systemic reactions to mosquito bites compared with control subjects with negative responses to laboratory-reared mosquito bites.

    Mean mosquito saliva–specific IgE levels in individuals with systemic reactions to mosquito bites compared with control subjects with negative responses to laboratory-reared mosquito bites.

  • Image Result

    Percentage of positivity of serum mosquito saliva–specific IgE and IgG in individuals with systemic allergic reactions and control subjects. Positivity was determined on the basis of the geometric mea

    Percentage of positivity of serum mosquito saliva–specific IgE and IgG in individuals with systemic allergic reactions and control subjects. Positivity was determined on the basis of the geometric mean of negative control subjects plus 1 SD.

 Supported by the Children's Hospital Foundation of Manitoba, Inc, and the Paul H. T. Thorlakson Research Fund for Andrew Beckett's BSc medicine studentship.

PII: S0091-6749(04)02218-3

doi: 10.1016/j.jaci.2004.08.014

The Journal of Allergy and Clinical Immunology
Volume 114, Issue 5 , Pages 1189-1194 , November 2004