The Journal of Allergy and Clinical Immunology
Volume 114, Issue 2 , Pages 387-391 , August 2004

Determination of food specific IgE levels over time can predict the development of tolerance in cow's milk and hen's egg allergy

Received 1 December 2003 ,Revised 12 April 2004 ,Accepted 14 April 2004.

References 

  1. Sampson HA. Food allergy. Part 1: immunopathogenesis and clinical disorders. J Allergy Clin Immunol. 1999;103:717–728
  2. Host A, Halken S, Jacobsen HP, Christensen AE, Herskind AM, Plesner K. Clinical course of cow's milk protein allergy/intolerance and atopic diseases in childhood. Pediatr Allergy Immunol. 2002;13(Suppl 15):23–28
  3. Boyano-Martinez T, Garcia-Ara C, Diaz-Pena JM, Martin-Esteban M. Prediction of tolerance on the basis of quantification of egg white-specific IgE antibodies in children with egg allergy. J Allergy Clin Immunol. 2002;110:304–309
  4. James JM, Sampson HA. Immunologic changes associated with the development of tolerance in children with cow milk allergy. J Pediatr. 1992;121:371–377
  5. Sicherer SH, Sampson HA. Cow's milk protein-specific IgE concentrations in two age groups of milk-allergic children and in children achieving clinical tolerance. Clin Exp Allergy. 1999;29:507–512
  6. Skolnick HS, Conover-Walker MK, Koerner CB, Sampson HA, Burks W, Wood RA. The natural history of peanut allergy. J Allergy Clin Immunol. 2001;107:367–374
  7. Jarvinen KM, Beyer K, Vila L, Chatchatee P, Busse PJ, Sampson HA. B-cell epitopes as a screening instrument for persistent cow's milk allergy. J Allergy Clin Immunol. 2002;110:293–297
  8. Sampson HA. Food allergy. Part 2: diagnosis and management. J Allergy Clin Immunol. 1999;103:981–989
  9. Sampson H. Diagnosing food allergy. In:  Spector S editors. Provocation testing in clinical practice. New York: Marcel Dekker, Inc; 1995;p. 623–646
  10. Sampson HA, Ho DG. Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents. J Allergy Clin Immunol. 1997;100:444–451
  11. Henderson CE, Ownby D, Klebanoff M, Levine RJ. Stability of immunoglobulin E (IgE) in stored obstetric sera. J Immunol Methods. 1998;213:99–101
  12. Sampson HA. Utility of food-specific IgE concentrations in predicting symptomatic food allergy. J Allergy Clin Immunol. 2001;107:891–896
  13. Hill DJ, Firer MA, Ball G, Hosking CS. Natural history of cows' milk allergy in children: immunological outcome over 2 years. Clin Exp Allergy. 1993;23:124–131
  14. Bernhisel-Broadbent J, Dintzis HM, Dintzis RZ, Sampson HA. Allergenicity and antigenicity of chicken egg ovomucoid (Gal d III) compared with ovalbumin (Gal d I) in children with egg allergy and in mice. J Allergy Clin Immunol. 1994;93:1047–1059
  15. Eggleston PA. Prospective studies in the natural history of food allergy. Ann Allergy. 1987;59:179–182
  16. Chatchatee P, Jarvinen KM, Bardina L, Beyer K, Sampson HA. Identification of IgE- and IgG-binding epitopes on alpha(s1)-casein: differences in patients with persistent and transient cow's milk allergy. J Allergy Clin Immunol. 2001;107:379–383
  17. Chatchatee P, Jarvinen KM, Bardina L, Vila L, Beyer K, Sampson HA. Identification of IgE and IgG binding epitopes on beta- and kappa-casein in cow's milk allergic patients. Clin Exp Allergy. 2001;31:1256–1262
  18. Vila L, Beyer K, Jarvinen KM, Chatchatee P, Bardina L, Sampson HA. Role of conformational and linear epitopes in the achievement of tolerance in cow's milk allergy. Clin Exp Allergy. 2001;31:1599–1606
  19. Host A, Halken S. A prospective study of cow milk allergy in Danish infants during the first 3 years of life. Clinical course in relation to clinical and immunological type of hypersensitivity reaction. Allergy. 1990;45:587–596

☆ This study was funded by a grant from the NIH, NIAID AI44236 and DRR M01-RR-00071. The reagents were provided by Pharmacia AB Diagnostics (Uppsala, Sweden).Disclosure of potential conflict of interest: L.P.C. Shek—none disclosed. L. Soderstrom is employed by Pharmacia Diagnostics AB. K. Beyer—none disclosed. S. Ahlstedt is employed by Pharmacia Diagnostics AB. H.A. Sampson is a consultant to Seer Pharmaceuticals, Inc, receives grants/research support from NIAD, Pharmacia Diagnostics, AB, Uppsala, Sweden, and is employed by Mount Sinai School of Medicine.

PII: S0091-6749(04)01402-2

doi: 10.1016/j.jaci.2004.04.032

The Journal of Allergy and Clinical Immunology
Volume 114, Issue 2 , Pages 387-391 , August 2004

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