The Journal of Allergy and Clinical Immunology
Volume 113, Issue 5 , Page 831, May 2004

A classification of plant food allergens

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1. Instructions for category 1 continuing medical education credit 

The American Academy of Allergy, Asthma and Immunology is accredited as a provider of Continuing Medical Education (CME) by the Accreditation Council for Continuing Medical Education.

Test ID no.: mai0033

Contact hours: 1.0

Expiration date: April 30, 2005

Category 1 credit can be earned by reading the text material and taking this CME examination online. For complete instructions, visit the Journal's Web site at www.mosby.com/jaci.

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2. Learning objectives: “a classification of plant food allergens” 

1.To understand the concept of a classification of allergens based on sequence and structural similarity and on function.

2.To identify the most important plant protein families and superfamilies that contain food allergens.

3.To consider the link between physicochemical properties, biochemical functions and allergenic activities of proteins.

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3. CME items 

Question 1. Which peanut allergen forms highly stable trimers that are protected from heat denaturation and gastric digestion?

A.Ara h 1

B.Ara h 2

C.Ara h 5

D.Ara h 7

Question 2. Which group of allergens is responsible for cases of Rosaceae fruit allergy that are not associated with pollen allergy?

A.Bet v 1–homologous proteins

B.profilins

C.2S albumins

D.nonspecific lipid transfer proteins

Question 3. What is the name of the protein superfamily that contains lipid transfer proteins, 2S albumins, and α-amylase/trypsin inhibitors?

A.cupins

B.prolamins

C.pathogenesis-related proteins

D.profilins

Question 4. What is the common property of 2S albumins, thaumatin-like proteins, and class I chitinases that is assumed to make an important contribution to the allergenicity of these proteins?

A.They are glycoproteins.

B.Their structures are stabilized by several disulfide bonds.

C.They have molecular masses of less than 10 kd.

D.They possess protease activity.

PII: S0091-6749(04)01003-6

doi:10.1016/j.jaci.2004.02.019

The Journal of Allergy and Clinical Immunology
Volume 113, Issue 5 , Page 831, May 2004