The Journal of Allergy and Clinical Immunology
Volume 113, Issue 3 , Pages 420-426 , March 2004

Clinical deterioration in pediatric asthmatic patients after September 11, 2001

  • Anthony M Szema, MD

      Affiliations

    • Department of Medicine, State University of New York at Stony Brook School of Medicine, Stony Brook, NY, USA
    • Corresponding Author InformationReprint requests: Anthony M. Szema, MD, Allergy and Asthma Center, Department of Medicine, T16, Room 041, SUNY Stony Brook School of Medicine, Stony Brook, NY 11794-8161
    • ,
  • Meera Khedkar, MD

      Affiliations

    • Department of Medicine, State University of New York at Stony Brook School of Medicine, Stony Brook, NY, USA
    • ,
  • Patrick F Maloney, MD

      Affiliations

    • Department of Medicine, State University of New York at Stony Brook School of Medicine, Stony Brook, NY, USA
    • ,
  • Patricia A Takach, MD

      Affiliations

    • Department of Medicine, State University of New York at Stony Brook School of Medicine, Stony Brook, NY, USA
    • ,
  • Michael S Nickels, MD, PhD

      Affiliations

    • Department of Medicine, State University of New York at Stony Brook School of Medicine, Stony Brook, NY, USA
    • ,
  • Harshit Patel, MD

      Affiliations

    • Department of Medicine, State University of New York at Stony Brook School of Medicine, Stony Brook, NY, USA
    • ,
  • Francesmary Modugno, PhD, MPH

      Affiliations

    • Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pa, USA
    • ,
  • Alan Y Tso, MD

      Affiliations

    • Charles B. Wang Community Health Center, New York, NY, USA
    • ,
  • Deborah H Lin, MD

      Affiliations

    • Charles B. Wang Community Health Center, New York, NY, USA

Received 14 October 2003 ,Revised 20 November 2003 ,Accepted 1 December 2003.

References 

    References
  1. McGee JK, Chen LC, Cohen MD, et al.  Chemical analysis of World Trade Center fine particulate matter for use in toxicological assessment. Environ Health Perspect. 2003;111:972–980
  2. Prezant DJ, Weiden M, Banauch GI, et al.  Cough and bronchial responsiveness in firefighters at the World Trade Center site. N Engl J Med. 2002;347:806–815
  3. Banauch GI, Alleyne D, Sanchez R, et al.  Persistent hyperreactivity and reactive airway dysfunction in firefighters at the World Trade Center. Am J Respir Crit Care Med. 2003;168:54–62
  4. Sly RM. Changing prevalence of allergic rhinitis and asthma. Ann Allergy Asthma Immunol. 1999;82:233–248
  5. Highlights of the expert panel report 2: guidelines for the diagnosis and management of asthma. Bethesda (MD): National Institutes of Health; 1997; NIH publication no. 97-4051A (3, 14, 16)
  6. Voter KZ, McBride JT. Diagnostic tests of lung function. Pediatr Rev. 1996;17:53–63
  7. Lioy P, Weisel CP, Millette JR, et al.  Characterization of the dust/smoke aerosol that settled east of the World Trade center (WTC) in Lower Manhattan after the collapse of the WTC 11 September 2001. Environ Health Perspect. 2002;110:703–712
  8. Gavett SH, Haykal-Coates N, Highfill HW, et al.  World Trade Center fine particulate matter causes respiratory tract hyperresponsiveness in mice. Environ Health Perspect. 2003;111:981–991
  9. Dockery DW, Speizer FE, Stram DO, Ware JH, Spengler JD, Ferris BG. Effects of inhalable particles on respiratory health of children. Am Rev Respir Dis. 1989;139:587–594
  10. Koenig JQ, Larson TV, Hanley QS, et al.  Pulmonary function changes in children associated with fine particulate matter. Environ Res. 1993;63:26–38
  11. D'Amato G, Liccardi G, D'Amato M, Cazzola M. The role of outdoor air pollution and climactic changes on the rising trends in respiratory allergy. Respir Med. 2001;95:606–611
  12. D'Amato G, Liccardi G, D'Amato M, Cazzola M. Outdoor air pollution, climactic changes and allergic bronchial asthma. Eur Respir J. 2002;20:763–776
  13. Teague WG, Bayer CW. Outdoor air pollution. Asthma and other concerns. Pediatr Clin North Am. 2001;48:1167–1183
  14. Update on asthma and air pollution research in inner cities [abstract]. Environ Health Perspect. 1999;107:617
  15. Goldsmith CA, Kobzik L. Particulate air pollution and asthma: a review of epidemiological and biological studies. Rev Environ Health. 1999;14:121–134
  16. van der Zee S, Hoek G, Boezen HM, Schouten JP, van Wijnen JH, Brunekreef B. Acute effects of urban air pollution on respiratory health of children with and without chronic respiratory symptoms. Occup En-viron Med. 1999;56:802–812
  17. Peden DB. Air pollution in asthma: effect of pollutants on airway inflammation. Ann Allergy Asthma Immunol. 2001;87(suppl 3):12–17
  18. Just J, Segala C, Sahraoui F, Priol G, Grimfeld A, Neukirch F. Short term Health effects of particulate and photochemical air pollution in asthmatic children. Eur Respir J. 2002;20:899–906
  19. Mortimer KM, Neas LM, Dockery DW, Redline S, Tager IB. The effect of air pollution on inner-city children with asthma. Eur Respir J. 2002;19:699–705
  20. Self-reported increase in asthma severity after the September 11 attacks on the World Trade Center—Manhattan, New York, 2001. MMWR Morb Mortal Wkly Rep. 2002;51:781–784
  21. von Klot S, Wolke G, Tuch T, et al.  Increased asthma medication use in association with ambient fine and ultrafine particles. Eur Respir J. 2002;20:691–702
  22. Higgins BG, Francis HC, Yates C, et al.  Environmental exposure to air pollution and allergens and peak flow changes. Eur Respir J. 2000;16:61–66
  23. National Asthma Education and Prevention Program . Expert Panel Report: guidelines for the diagnosis and management of asthma update on selected topics—2002 November 2002, part 2. J Allergy Clin Immunol. 2002;110(suppl):S141–S219
  24. Behrman RE, Kliegman RM, Jenson HB. In: Nelson textbook of pediatrics. 16th ed.. Philadephia: W.B. Saunders Co; 2000;p. 666
  25. Galea S, Ahern J, Resnick H, et al.  Psychological sequelae of the September 11 terrorist attacks in New York City. N Engl J Med. 2002;346:982–987
  26. Chen H, Chung H, Chen T, Fang L, Chen JP. The emotional distress in a community after the terrorist attack on the World Trade Center. Community Ment Health J. 2003;39:157–165
  27. Chen JP, Chen H, Chung H. Depressive disorders in Asian American Adults. West J Med. 2002;176:239–244
  28. Yeung A, Deguang H. Somatoform disorders. West J Med. 2002;176:253–256

☆ Supported by a research grant and medical student scholarships from the Chinese-American Medical Society, the SUNY Dean's Clinical Scholar Targeted Research Opportunities Award, the Allergy and Asthma Center of the Stony Brook Foundation, and the Howard Hughes Undergraduate Fellowship Award.Drs Szema, Khedkar, Maloney and Takach contributed equally to this study.

PII: S0091-6749(03)02777-5

doi: 10.1016/j.jaci.2003.12.015

The Journal of Allergy and Clinical Immunology
Volume 113, Issue 3 , Pages 420-426 , March 2004

Article Tools

* Image Usage & Resolution