The Journal of Allergy and Clinical Immunology
Volume 116, Issue 1 , Pages 223-225 , July 2005

Childhood cat exposure–related tolerance is associated with IL1A and IL10 polymorphisms

  • Jussi Karjalainen, MD, PhD

      Affiliations

    • Tampere University Hospital, Department of Respiratory Medicine
    • ,
  • Miia Virta, MD

      Affiliations

    • Department of Microbiology and Immunology, University of Tampere Medical School
    • ,
  • Tanja Pessi, PhD

      Affiliations

    • Department of Microbiology and Immunology, University of Tampere Medical School
    • ,
  • Janne Hulkkonen, MD, PhD

      Affiliations

    • Department of Microbiology and Immunology, University of Tampere Medical School
    • ,
  • Markku M. Nieminen, MD, PhD

      Affiliations

    • Tampere University Hospital, Department of Respiratory Medicine
    • ,
  • Mikko Hurme, MD, PhD

      Affiliations

    • Department of Microbiology and Immunology, University of Tampere Medical School
    • Tampere University Hospital, Centre for Laboratory Medicine, FIN-33014 Tampere, Finland

  • Image Result

    Proportion of cat-sensitized subjects with or without childhood exposure to cat in relation to IL1A (+4845G>T) genotype and IL10 haplotype GCC in asthmatic subjects (n=239), in control subjects (n=396

    Proportion of cat-sensitized subjects with or without childhood exposure to cat in relation to IL1A (+4845G>T) genotype and IL10 haplotype GCC in asthmatic subjects (n=239), in control subjects (n=396), and in all subjects (both asthmatic and control subjects) with a family history of allergy or asthma (n=128). P values were calculated with the χ2 test (df=1).

 Supported by the Academy of Finland, the Rehabilitation Funds of the Finnish Social Insurance Institution, the Medical Research Fund of Tampere University Hospital, and the Tampere Tuberculosis Foundation.

PII: S0091-6749(05)00603-2

doi: 10.1016/j.jaci.2005.03.026

The Journal of Allergy and Clinical Immunology
Volume 116, Issue 1 , Pages 223-225 , July 2005

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