The Journal of Allergy and Clinical Immunology
Volume 111, Issue 1 , Pages 66-71 , January 2003

Rhinovirus-induced wheezing in infancy—the first sign of childhood asthma?

Presented in part at the 19th Annual Meeting of the European Society for Pediatric Infectious Diseases, Istanbul, Turkey, March 26-28, 2001.

Received 28 April 2002 ,Revised 21 September 2002 ,Accepted 8 October 2002.

  • Image Result

    Subgroups of the children in the present study. The term frozen samples refers to frozen NPA specimens obtained during the index episode of wheezing in infancy. PCR tests were performed to identify RV

    Subgroups of the children in the present study. The term frozen samples refers to frozen NPA specimens obtained during the index episode of wheezing in infancy. PCR tests were performed to identify RVs, enteroviruses, and coronaviruses in these NPAs.

  • Image Result
    RV and RSV findings in 81 infants hospitalized for wheezing, presented in 4 age groups. The viral findings have been classified into 3 categories: RSV-positive, RV-positive, and other/no viral finding

    RV and RSV findings in 81 infants hospitalized for wheezing, presented in 4 age groups. The viral findings have been classified into 3 categories: RSV-positive, RV-positive, and other/no viral findings. In 1 case (in the 1-to-5-months age group), both RSV and RV were identified; in the bar graph, that case is included in the RV-positive group.

 Supported by the Foundation for Pediatric Research, Kuopio University Hospital (EVO grant, code 440054), and C.G. Sundell's Foundation.

☆☆ Reprint requests: Anne Kotaniemi-Syrjänen, MD, Department of Pediatrics, Kuopio University Hospital, PO Box 1777, FIN-70211 Kuopio, Finland.

PII: S0091-6749(02)91295-9

doi: 10.1067/mai.2003.33

The Journal of Allergy and Clinical Immunology
Volume 111, Issue 1 , Pages 66-71 , January 2003